Detalhe da pesquisa
1.
Mechanistic insights into inter-chain disulfide bond reduction of IgG1 and IgG4 antibodies.
Appl Microbiol Biotechnol
; 106(3): 1057-1066, 2022 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-35072737
2.
Understanding the pathway and kinetics of aspartic acid isomerization in peptide mapping methods for monoclonal antibodies.
Anal Bioanal Chem
; 413(8): 2113-2123, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-33543314
3.
Assessment of CE-based baseline disturbances using simulation and targeted experimental evaluation-impact on the purity determination of therapeutic proteins.
Anal Bioanal Chem
; 411(11): 2425-2437, 2019 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-30880351
4.
Therapeutic protein purity and fragmented species characterization by capillary electrophoresis sodium dodecyl sulfate using systematic hybrid cleavage and forced degradation.
Anal Bioanal Chem
; 411(21): 5617-5629, 2019 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-31214752
5.
Purity Determination by Capillary Electrophoresis Sodium Hexadecyl Sulfate (CE-SHS): A Novel Application For Therapeutic Protein Characterization.
Anal Chem
; 90(4): 2542-2547, 2018 02 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29357216
6.
Host Cell Protein Profiling by Targeted and Untargeted Analysis of Data Independent Acquisition Mass Spectrometry Data with Parallel Reaction Monitoring Verification.
Anal Chem
; 89(10): 5294-5302, 2017 05 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28402653
7.
A novel reagent significantly improved assay robustness in imaged capillary isoelectric focusing.
Anal Biochem
; 521: 1-7, 2017 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28065577
8.
Imaged capillary isoelectric focusing in native condition: A novel and successful example.
Anal Biochem
; 537: 13-19, 2017 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28844814
9.
Systematic Development of a Size Exclusion Chromatography Method for a Monoclonal Antibody with High Surface Aggregation Propensity (SAP) Index.
J Pharm Sci
; 110(7): 2651-2660, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33812889
10.
Design of next-generation therapeutic IgG4 with improved manufacturability and bioanalytical characteristics.
MAbs
; 12(1): 1829338, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33044887
11.
Streamlining the polishing step development process via physicochemical characterization of monoclonal antibody aggregates.
J Chromatogr A
; 1598: 101-112, 2019 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30954243
12.
Monoclonal antibody higher order structure analysis by high throughput protein conformational array.
MAbs
; 10(3): 397-405, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29313446
13.
Using hydrogen peroxide to prevent antibody disulfide bond reduction during manufacturing process.
MAbs
; 10(3): 500-510, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29336721
14.
Process analytics for purification of monoclonal antibodies.
J Chromatogr B Analyt Technol Biomed Life Sci
; 848(1): 79-87, 2007 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17161664
15.
Optimization of microchip-based electrophoresis for monoclonal antibody product quality analysis revealed needs for extra surfactants during denaturation.
J Pharm Biomed Anal
; 120: 46-56, 2016 Feb 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-26704629