Detalhe da pesquisa
1.
Gedatolisib in combination with palbociclib and endocrine therapy in women with hormone receptor-positive, HER2-negative advanced breast cancer: results from the dose expansion groups of an open-label, phase 1b study.
Lancet Oncol
; 25(4): 474-487, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38547892
2.
A Phase 1B open-label study of gedatolisib (PF-05212384) in combination with other anti-tumour agents for patients with advanced solid tumours and triple-negative breast cancer.
Br J Cancer
; 128(1): 30-41, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36335217
3.
Correction to: A Phase 1B open-label study of gedatolisib (PF-05212384) in combination with other anti-tumour agents for patients with advanced solid tumours and triple-negative breast cancer.
Br J Cancer
; 128(2): 400, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-36697966
4.
Pharmacologic inhibition of S-nitrosoglutathione reductase protects against experimental asthma in BALB/c mice through attenuation of both bronchoconstriction and inflammation.
BMC Pulm Med
; 14: 3, 2014 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24405692
5.
Structure-activity relationship of pyrrole based S-nitrosoglutathione reductase inhibitors: carboxamide modification.
Bioorg Med Chem Lett
; 22(6): 2338-42, 2012 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22342142
6.
Structure-activity relationships of pyrrole based S-nitrosoglutathione reductase inhibitors: pyrrole regioisomers and propionic acid replacement.
Bioorg Med Chem Lett
; 21(12): 3671-5, 2011 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21570838
7.
Discovery of potent and novel S-nitrosoglutathione reductase inhibitors devoid of cytochrome P450 activities.
Bioorg Med Chem Lett
; 21(19): 5849-53, 2011 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21855338
8.
Pharmacological inhibition of S-nitrosoglutathione reductase improves endothelial vasodilatory function in rats in vivo.
J Appl Physiol (1985)
; 114(6): 752-60, 2013 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23349456
9.
ADH IB expression, but not ADH III, is decreased in human lung cancer.
PLoS One
; 7(12): e52995, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23285246
10.
Discovery of s-nitrosoglutathione reductase inhibitors: potential agents for the treatment of asthma and other inflammatory diseases.
ACS Med Chem Lett
; 2(5): 402-6, 2011 May 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900320
11.
Identification of nuclear export inhibitors with potent anticancer activity in vivo.
Cancer Res
; 69(2): 510-7, 2009 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19147564
12.
Heterologous production of epothilone C and D in Escherichia coli.
Biochemistry
; 45(4): 1321-30, 2006 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-16430229
13.
Metabolic pathway engineering for complex polyketide biosynthesis in Saccharomyces cerevisiae.
FEMS Yeast Res
; 6(1): 40-7, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16423069