Detalhe da pesquisa
1.
Multiplex Hybrid Antigen-Capture LC-MRM Quantification in Sera and Nasal Lining Fluid of AZD7442, a SARS-CoV-2-Targeting Antibody Combination.
Anal Chem
; 94(43): 14835-14845, 2022 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36269894
2.
Intact quantitative bioanalytical method development and fit-for-purpose validation of a monoclonal antibody and its related fab fragment in human vitreous and aqueous humor using LC-HRMS.
Anal Bioanal Chem
; 414(14): 4189-4202, 2022 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-35451621
3.
Multifaceted Bioanalytical Methods for the Comprehensive Pharmacokinetic and Catabolic Assessment of MEDI3726, an Anti-Prostate-Specific Membrane Antigen Pyrrolobenzodiazepine Antibody-Drug Conjugate.
Anal Chem
; 92(16): 11135-11144, 2020 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32459957
4.
Comprehensive performance evaluation of ligand-binding assay-LC-MS/MS method for co-dosed monoclonal anti-SARS-CoV-2 antibodies (AZD7442).
Bioanalysis
; 16(7): 149-163, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38385904
5.
Comparison of methods for quantitative analysis of ranibizumab and bevacizumab in human plasma using various bioanalytical techniques, including microfluidic immunoassay, triple quadrupole, and high-resolution liquid chromatography-tandem mass spectrometry approaches.
J Pharm Biomed Anal
; 217: 114823, 2022 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35576733
6.
Optimization and method validation for the quantitative analysis of a monoclonal antibody and its related fab fragment in human plasma after intravitreal administration, using LC-MS/MS.
J Chromatogr B Analyt Technol Biomed Life Sci
; 1164: 122474, 2021 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33508760
7.
Multiplex LC-MS/MS Assays for Clinical Bioanalysis of MEDI4276, an Antibody-Drug Conjugate of Tubulysin Analogue Attached via Cleavable Linker to a Biparatopic Humanized Antibody against HER-2.
Antibodies (Basel)
; 8(1)2019 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31544817
8.
Simultaneous determination of intracellular concentrations of tenofovir, emtricitabine, and dolutegravir in human brain microvascular endothelial cells using liquid chromatography-tandem mass spectrometry (LC-MS/MS).
Anal Chim Acta
; 1056: 79-87, 2019 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30797464
9.
Immunoaffinity LC-MS/MS to quantify a PEGylated anti-Factor D Fab biotherapeutic in cynomolgus monkey serum.
Bioanalysis
; 11(23): 2161-2173, 2019 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-31701759
10.
Cell-type specific differences in antiretroviral penetration and the effects of HIV-1 Tat and morphine among primary human brain endothelial cells, astrocytes, pericytes, and microglia.
Neurosci Lett
; 712: 134475, 2019 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31491466
11.
Preanalytical approaches to improve recovery of amyloid-ß peptides from CSF as measured by immunological or mass spectrometry-based assays.
Alzheimers Res Ther
; 10(1): 118, 2018 11 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30486870
12.
Validation of a biotherapeutic immunoaffinity-LC-MS/MS assay in monkey serum: 'plug-and-play' across seven molecules.
Bioanalysis
; 8(15): 1565-1577, 2016 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-27396481
13.
Do we have a mature LC-MS/MS methodology for therapeutic monoclonal antibody bioanalysis?
Bioanalysis
; 9(17): 1289-1292, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28901174