Detalhe da pesquisa
1.
A 10-step framework for use of read-across (RAX) in next generation risk assessment (NGRA) for cosmetics safety assessment.
Regul Toxicol Pharmacol
; 129: 105094, 2022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-34990780
2.
Read-across and new approach methodologies applied in a 10-step framework for cosmetics safety assessment - A case study with parabens.
Regul Toxicol Pharmacol
; 132: 105161, 2022 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-35508214
3.
A strategy for safety assessment of chemicals with data gaps for developmental and/or reproductive toxicity.
Regul Toxicol Pharmacol
; 72(2): 202-15, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25910676
4.
Framework for identifying chemicals with structural features associated with the potential to act as developmental or reproductive toxicants.
Chem Res Toxicol
; 26(12): 1840-61, 2013 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-24206190
5.
Identifying chemicals based on receptor binding/bioactivation/mechanistic explanation associated with potential to elicit hepatotoxicity and to support structure activity relationship-based read-across.
Curr Res Toxicol
; 5: 100108, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37363741
6.
Structure-activity relationship read-across and transcriptomics for branched carboxylic acids.
Toxicol Sci
; 191(2): 343-356, 2023 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36583546
7.
Effects of transplacental 17-α-ethynyl estradiol or bisphenol A on the developmental profile of steroidogenic acute regulatory protein in the rat testis.
Birth Defects Res B Dev Reprod Toxicol
; 95(4): 318-25, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22752971
8.
Article title: Transcriptional profiling efficacy to define biological activity similarity for cosmetic ingredients' safety assessment based on next-generation read-across.
Front Toxicol
; 4: 1082222, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36618549
9.
Case studies to test: A framework for using structural, reactivity, metabolic and physicochemical similarity to evaluate the suitability of analogs for SAR-based toxicological assessments.
Regul Toxicol Pharmacol
; 60(1): 120-35, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21420459
10.
Predicting developmental toxicity through toxicogenomics.
Birth Defects Res C Embryo Today
; 90(2): 110-7, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20544695
11.
Incorporation of in vitro techniques for botanicals dietary supplement safety assessment - Towards evaluation of developmental and reproductive toxicity (DART).
Food Chem Toxicol
; 144: 111539, 2020 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-32645467
12.
Use of connectivity mapping to support read across: A deeper dive using data from 186 chemicals, 19 cell lines and 2 case studies.
Toxicology
; 423: 84-94, 2019 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31125584
13.
Letter to the editor.
Toxicol Sci
; 191(1): 192, 2023 01 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-36269224
14.
Uterine temporal response to acute exposure to 17alpha-ethinyl estradiol in the immature rat.
Toxicol Sci
; 97(2): 467-90, 2007 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-17351261
15.
Dose- and Time-Dependent Transcriptional Response of Ishikawa Cells Exposed to Genistein.
Toxicol Sci
; 151(1): 71-87, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26865667
16.
Grouping 34 Chemicals Based on Mode of Action Using Connectivity Mapping.
Toxicol Sci
; 151(2): 447-61, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27026708
17.
Toward Good Read-Across Practice (GRAP) guidance.
ALTEX
; 33(2): 149-66, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26863606
18.
Design of a microsphere-based high-throughput gene expression assay to determine estrogenic potential.
Environ Health Perspect
; 113(9): 1164-71, 2005 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16140622
19.
Gene expression changes induced in the testis by transplacental exposure to high and low doses of 17{alpha}-ethynyl estradiol, genistein, or bisphenol A.
Toxicol Sci
; 86(2): 396-416, 2005 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-15901920
20.
Gene expression changes related to growth and differentiation in the fetal and juvenile reproductive system of the female rat: evaluation of microarray results.
Reprod Toxicol
; 19(3): 381-94, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-15686872