Detalhe da pesquisa
1.
Hydrophobicity Tuning of Cationic Polyaspartamide Derivatives for Enhanced Antisense Oligonucleotide Delivery.
Bioconjug Chem
; 35(2): 125-131, 2024 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38290165
2.
Preferential delivery of lipid-ligand conjugated DNA/RNA heteroduplex oligonucleotide to ischemic brain in hyperacute stage.
Mol Ther
; 31(4): 1106-1122, 2023 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36694463
3.
Quantitative Model Analysis and Simulation of Pharmacokinetics and Metastasis-Associated Lung Adenocarcinoma 1 RNA Knockdown Effect After Systemic Administration of Cholesterol-Conjugated DNA/RNA Heteroduplex Oligonucleotide Crossing Blood-Brain Barrier of Mice.
J Pharmacol Exp Ther
; 384(1): 197-204, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36273821
4.
Effects of combinations of gapmer antisense oligonucleotides on the target reduction.
Mol Biol Rep
; 50(4): 3539-3546, 2023 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-36787053
5.
Regulation of activated microglia and macrophages by systemically administered DNA/RNA heteroduplex oligonucleotides.
Mol Ther
; 30(6): 2210-2223, 2022 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35189344
6.
Peripheral administration of nanomicelle-encapsulated anti-Aß oligomer fragment antibody reduces various toxic Aß species in the brain.
J Nanobiotechnology
; 21(1): 36, 2023 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-36721182
7.
Short DNA/RNA heteroduplex oligonucleotide interacting proteins are key regulators of target gene silencing.
Nucleic Acids Res
; 49(9): 4864-4876, 2021 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33928345
8.
Efficient Gene Suppression by DNA/DNA Double-Stranded Oligonucleotide In Vivo.
Mol Ther
; 29(2): 838-847, 2021 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33290725
9.
2',4'-BNA/LNA with 9-(2-Aminoethoxy)-1,3-diaza-2-oxophenoxazine Efficiently Forms Duplexes and Has Enhanced Enzymatic Resistance*.
Chemistry
; 27(7): 2427-2438, 2021 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33280173
10.
Highly efficient silencing of microRNA by heteroduplex oligonucleotides.
Nucleic Acids Res
; 47(14): 7321-7332, 2019 08 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31214713
11.
Noncovalent Stabilization of Vesicular Polyion Complexes with Chemically Modified/Single-Stranded Oligonucleotides and PEG-b-guanidinylated Polypeptides for Intracavity Encapsulation of Effector Enzymes Aimed at Cooperative Gene Knockdown.
Biomacromolecules
; 21(10): 4365-4376, 2020 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32924444
12.
Efficacy of Multi-exon Skipping Treatment in Duchenne Muscular Dystrophy Dog Model Neonates.
Mol Ther
; 27(1): 76-86, 2019 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30448197
13.
Effects of systemic multiexon skipping with peptide-conjugated morpholinos in the heart of a dog model of Duchenne muscular dystrophy.
Proc Natl Acad Sci U S A
; 114(16): 4213-4218, 2017 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28373570
14.
Synthesis of 2'-O-(N-methylcarbamoylethyl) 5-methyl-2-thiouridine and its application to splice-switching oligonucleotides.
Bioorg Med Chem Lett
; 29(2): 160-163, 2019 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30551900
15.
Truncated dystrophin ameliorates the dystrophic phenotype of mdx mice by reducing sarcolipin-mediated SERCA inhibition.
Biochem Biophys Res Commun
; 505(1): 51-59, 2018 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30236982
16.
A Cocatalyst that Stabilizes a Hydride Intermediate during Photocatalytic Hydrogen Evolution over a Rhodium-Doped TiO2 Nanosheet.
Angew Chem Int Ed Engl
; 57(29): 9073-9077, 2018 Jul 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29766627
17.
Serum Osteopontin as a Novel Biomarker for Muscle Regeneration in Duchenne Muscular Dystrophy.
Am J Pathol
; 186(5): 1302-12, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26963343
18.
Synthesis and thermal stabilities of oligonucleotides containing 2'-O,4'-C-methylene bridged nucleic acid with a phenoxazine base.
Org Biomol Chem
; 15(38): 8145-8152, 2017 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28920119
19.
Three classical Cepheid variable stars in the nuclear bulge of the Milky Way.
Nature
; 477(7363): 188-90, 2011 Aug 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-21866100
20.
Endogenous Multiple Exon Skipping and Back-Splicing at the DMD Mutation Hotspot.
Int J Mol Sci
; 17(10)2016 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-27754374