Detalhe da pesquisa
1.
rs10924104 in the expression enhancer motif of CD58 confers susceptibility to human autoimmune diseases.
Hum Genet
; 143(1): 19-33, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37994973
2.
rs2013278 in the multiple immunological-trait susceptibility locus CD28 regulates the production of non-functional splicing isoforms.
Hum Genomics
; 16(1): 46, 2022 10 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36271469
3.
Design and synthesis of 6-methylpyridin-2-one derivatives as novel and potent GluN2A positive allosteric modulators for the treatment of cognitive impairment.
Bioorg Med Chem
; 79: 117150, 2023 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36640594
4.
X Chromosome Contribution to the Genetic Architecture of Primary Biliary Cholangitis.
Gastroenterology
; 160(7): 2483-2495.e26, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33675743
5.
rs9459874 and rs1012656 in CCR6/FGFR1OP confer susceptibility to primary biliary cholangitis.
J Autoimmun
; 126: 102775, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34864633
6.
An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs.
J Hepatol
; 75(3): 572-581, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34033851
7.
A 12-kb structural variation in progressive myoclonic epilepsy was newly identified by long-read whole-genome sequencing.
J Hum Genet
; 64(5): 359-368, 2019 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-30760880
8.
Corrigendum to: "An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs" [J Hepatol 75 (2021) 572-581].
J Hepatol
; 78(4): 883, 2023 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-36639314
9.
Association of a single nucleotide polymorphism in TNIP1 with type-1 autoimmune hepatitis in the Japanese population.
J Hum Genet
; 63(6): 739-744, 2018 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-29559739
10.
Discovery of 1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazoles as novel class of corticotropin releasing factor 1 receptor antagonists.
Bioorg Med Chem
; 26(9): 2229-2250, 2018 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29459145
11.
Corrigendum to 'An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs' [J Hepatol 2021;75(3):572-581].
J Hepatol
; 76(2): 489, 2022 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-34895949
12.
Association of a single nucleotide polymorphism upstream of ICOS with Japanese autoimmune hepatitis type 1.
J Hum Genet
; 62(4): 481-484, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-27974812
13.
Hydrophobic bile acids suppress expression of AE2 in biliary epithelial cells and induce bile duct inflammation in primary biliary cholangitis.
J Autoimmun
; 75: 150-160, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27592379
14.
Natural killer cells regulate T cell immune responses in primary biliary cirrhosis.
Hepatology
; 62(6): 1817-27, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26264889
15.
Discovery of novel 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine derivatives as γ-secretase modulators (Part 2).
Bioorg Med Chem
; 24(14): 3192-206, 2016 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27255179
16.
Hepatic flares promote rapid decline of serum hepatitis B surface antigen (HBsAg) in patients with HBsAg seroclearance: A long-term follow-up study.
Hepatol Res
; 46(3): E89-99, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25951079
17.
Human primary biliary cirrhosis-susceptible allele of rs4979462 enhances TNFSF15 expression by binding NF-1.
Hum Genet
; 134(7): 737-47, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25899471
18.
Genome-wide association study identifies TNFSF15 and POU2AF1 as susceptibility loci for primary biliary cirrhosis in the Japanese population.
Am J Hum Genet
; 91(4): 721-8, 2012 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-23000144
19.
Disease susceptibility genes shared by primary biliary cirrhosis and Crohn's disease in the Japanese population.
J Hum Genet
; 60(9): 525-31, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26084578
20.
Discovery of novel 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine derivatives as γ-secretase modulators.
Bioorg Med Chem Lett
; 25(19): 4245-9, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26298496