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Patient-reported outcome measures (PROMs) are a vital part of the toolkit for the current practice of orthopedic surgery. We are witnessing the expansion of the use of PROMs in clinical practice and in research; the ultimate direction of this expansion is unclear. The purpose of this systematic review was to identify the trends in the use of PROMs in major upper limb publications over a 7-year period. We retrospectively reviewed all articles published in 6 of the most influential upper limb orthopedic journals based on impact factor from January 2013 to January 2020. PubMed, Medline, and Embase were used to access the abstracts for all articles published for this period. We included all articles related to shoulder arthroplasty, shoulder instability, rotator cuff surgery, and involving the use of PROMs. There were 4175 articles identified from the selected journals over the chosen time period, of which 607 were eligible for inclusion in the study. The number of articles reporting PROMs increased from 57 in 2013 to 115 in 2019, which was a 102% increase. The total number of PROM usages recorded was 1593 which was comprised of 63 different scoring systems, with each article using a median of 3 different PROMs. The most commonly used score in articles originating from North America was the American Shoulder and Elbow Surgeons score (216 uses in 273 articles; 78.1%), from Europe it was the Constant-Murley Score (129 uses in 183 articles; 70.4%), and from Asia it was the American Shoulder and Elbow Surgeons score (80 uses in 126 articles; 63.4%). The use of PROMs is evolving with an increasing prevalence of and diversity of PROMs being used in upper limb surgery. There is geographical variation in the use of PROMs, and a variety of systems used, with only 3 of the top 10 most used PROMs reporting on patient satisfaction or wellbeing. Given that a diverse range of PROMs study a diverse range of conditions and procedures, there may not be a need for a consensus on the best overall use of PROMs, but there may be ideal PROMs suited to answer specific questions.
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Many factors may trigger intervertebral disc (IVD) structural failure (intervertebral disc degeneration (IDD) and endplate changes), including inflammation, infection, dysbiosis, and the downstream effects of chemical factors. Of these, microbial diversity in the IVD and elsewhere in the body has been considered as one of the potential reasons for disc structural failure. The exact relationships between microbial colonization and IVD structural failure are not well understood. This meta-analysis aimed to investigate the impact of microbial colonization and its location (such as skin, IVD, muscle, soft tissues, and blood) on IVD structural failure and corresponding low back pain (LBP) if any. We searched four online databases for potential studies. The potential relationships between microbial colonization in different sample sources (such as skin, IVD, muscle, soft tissues, and blood) and IDD and endplate change were considered as primary outcomes. Odds ratio (OR) and 95% confidence intervals (CI) for direct comparisons were reported. Grading of Recommendations Assessment, Development and Evaluation (GRADE) scale was used to assess the quality of evidence. Twenty-five cohort studies met the selection criteria. Overall pooled prevalence of microbial colonization in 2419 patients with LBP was 33.2% (23.6%-43.6%). The pooled prevalence of microbial colonization in 2901 samples was 29.6% (21.0%-38.9%). Compared with the patients without endplate change, the patients with endplate changes had higher rates of microbial colonization of disc (OR = 2.83; 95% CI = 1.93-4.14; I 2 = 37.6%; p = 0.108). The primary pathogen was Cutibacterium acnes which was present in 22.2% of cases (95% CI = 13.3%-32.5%; I 2 = 96.6%; p = 0.000). This meta-analysis and systematic review found low-quality grade evidence for an association between microbial colonization of disc with endplate changes. The primary pathogen was C. acnes. Due to lack of enough high-quality studies and methodological limitations of this review, further studies are required to improve our understanding of the potential relationships and mechanisms of microbiota, dysbiosis, IVD colonization and IVD structural failure.
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Eight Thiel embalmed hips were dissected. The distance between the sciatic nerve and the femoral neck was measured before and after hip dislocation, and before and after release of the gluteus maximus tendon. There was a significant reduction in the mean distance between the neck of femur and the sciatic nerve in both the gluteus maximus tendon release and the unreleased groups at 60° and 90° of hip flexion, p < 0.05. The mean distance between the neck of femur and sciatic nerve was greater in the release group for all positions.
RESUMO
INTRODUCTION: Internal or external fixation of the femur is common following trauma. Neurovascular structures around the shaft of the femur are at risk, particularly the superficial femoral artery (SFA). Damage to this structure, when it is medial to the femur, can occur during the lateral approach, when drills, pins or screws are inserted. This anatomical study aims to delineate a safe zone for operative intervention to the shaft of the femur with respect to the SFA, and describe the relationship between this zone and the width and length of the femur. MATERIALS AND METHODS: 41 limbs from 22 patients were examined using Computed Tomography Angiography to determine the relationship between the SFA and the medial shaft of the femur. The danger zone where the SFA lies medial to the shaft of the femur in the sagittal plane was identified and measured, and the width and length of the femur were measured for reference points. RESULTS: The SFA begins anterior to the shaft of the femur proximally and passes posteriorly, crossing the shaft of the femur in the sagittal plane at points 239.6±39.8mm and 172.5±40.9mm proximal to the adductor tubercle (AT). The width of the femur correlates to the inferior crossing point of the SFA on the femur with a mean ratio of 1:2.05, p=0.000, the length of the femur correlates to the mid crossing point of the SFA on the femur with a ratio of 2.00:1, p=0.000. CONCLUSIONS: There is a safe zone along the medial shaft of the femur, which can be estimated intraoperatively using anatomical reference points.