Detalhe da pesquisa
1.
SARS-CoV-2 infection is effectively treated and prevented by EIDD-2801.
Nature
; 591(7850): 451-457, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33561864
2.
Influenza A virus resistance to 4'-fluorouridine coincides with viral attenuation in vitro and in vivo.
PLoS Pathog
; 20(2): e1011993, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38300953
3.
Modeling Heartland virus disease in mice and therapeutic intervention with 4'-fluorouridine.
J Virol
; 98(4): e0013224, 2024 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38511932
4.
4'-Fluorouridine mitigates lethal infection with pandemic human and highly pathogenic avian influenza viruses.
PLoS Pathog
; 19(4): e1011342, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37068076
5.
Therapeutic targeting of measles virus polymerase with ERDRP-0519 suppresses all RNA synthesis activity.
PLoS Pathog
; 17(2): e1009371, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33621266
6.
Analysis of the Potential for N4-Hydroxycytidine To Inhibit Mitochondrial Replication and Function.
Antimicrob Agents Chemother
; 64(2)2020 01 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31767721
7.
Small-Molecule Antiviral ß-d-N4-Hydroxycytidine Inhibits a Proofreading-Intact Coronavirus with a High Genetic Barrier to Resistance.
J Virol
; 93(24)2019 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31578288
8.
ß-d-N4-Hydroxycytidine Is a Potent Anti-alphavirus Compound That Induces a High Level of Mutations in the Viral Genome.
J Virol
; 92(3)2018 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29167335
9.
Orally Efficacious Broad-Spectrum Ribonucleoside Analog Inhibitor of Influenza and Respiratory Syncytial Viruses.
Antimicrob Agents Chemother
; 62(8)2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29891600
10.
Identification and Characterization of Influenza Virus Entry Inhibitors through Dual Myxovirus High-Throughput Screening.
J Virol
; 90(16): 7368-7387, 2016 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27252534
11.
4'-Fluorouridine inhibits alphavirus replication and infection in vitro and in vivo.
mBio
; : e0042024, 2024 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38700353
12.
Therapeutic mitigation of measles-like immune amnesia and exacerbated disease after prior respiratory virus infections in ferrets.
Nat Commun
; 15(1): 1189, 2024 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38331906
13.
Asymmetric synthesis of host-directed inhibitors of myxoviruses.
Beilstein J Org Chem
; 9: 197-203, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23400228
14.
The prophylactic and therapeutic efficacy of the broadly active antiviral ribonucleoside N4-Hydroxycytidine (EIDD-1931) in a mouse model of lethal Ebola virus infection.
Antiviral Res
; 209: 105453, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36379378
15.
Influenza A virus resistance to 4'-fluorouridine coincides with viral attenuation in vitro and in vivo.
bioRxiv
; 2023 Oct 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37905070
16.
Comparing molnupiravir and nirmatrelvir/ritonavir efficacy and the effects on SARS-CoV-2 transmission in animal models.
Nat Commun
; 14(1): 4731, 2023 08 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37550333
17.
Design and Optimization of Novel Competitive, Non-peptidic, SARS-CoV-2 Mpro Inhibitors.
ACS Med Chem Lett
; 14(10): 1434-1440, 2023 Oct 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37849558
18.
SARS-CoV-2 variant of concern type and biological sex affect efficacy of molnupiravir in dwarf hamster model of severe COVID-19.
bioRxiv
; 2022 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35169793
19.
Orally efficacious lead of the AVG inhibitor series targeting a dynamic interface in the respiratory syncytial virus polymerase.
Sci Adv
; 8(25): eabo2236, 2022 06 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35749502
20.
SARS-CoV-2 VOC type and biological sex affect molnupiravir efficacy in severe COVID-19 dwarf hamster model.
Nat Commun
; 13(1): 4416, 2022 07 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35906230