Detalhe da pesquisa
1.
Specific Inhibition of Hepatic Lactate Dehydrogenase Reduces Oxalate Production in Mouse Models of Primary Hyperoxaluria.
Mol Ther
; 26(8): 1983-1995, 2018 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29914758
2.
Inhibition of Glycolate Oxidase With Dicer-substrate siRNA Reduces Calcium Oxalate Deposition in a Mouse Model of Primary Hyperoxaluria Type 1.
Mol Ther
; 24(4): 770-8, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26758691
3.
Discovery and characterization of orthosteric and allosteric muscarinic M2 acetylcholine receptor ligands by affinity selection-mass spectrometry.
J Biomol Screen
; 11(2): 194-207, 2006 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-16490772
4.
Formal synthesis of merrilactone A using a domino cyanide 1,4-addition-aldol cyclization.
Org Lett
; 14(14): 3720-3, 2012 Jul 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-22770228
5.
Discovery of a 5H-benzo[4,5]cyclohepta[1,2-b]pyridin-5-one (MK-2461) inhibitor of c-Met kinase for the treatment of cancer.
J Med Chem
; 54(12): 4092-108, 2011 Jun 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-21608528
6.
Inhibitors of the lipid phosphatase SHIP2 discovered by high-throughput affinity selection-mass spectrometry screening of combinatorial libraries.
Comb Chem High Throughput Screen
; 12(8): 760-71, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19531013
7.
The discovery of 6-amino nicotinamides as potent and selective histone deacetylase inhibitors.
Bioorg Med Chem Lett
; 17(19): 5300-9, 2007 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17761416
8.
A general technique to rank protein-ligand binding affinities and determine allosteric versus direct binding site competition in compound mixtures.
J Am Chem Soc
; 126(47): 15495-503, 2004 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15563178