Detalhe da pesquisa
1.
Overexpression and knockout of miR-126 both promote leukemogenesis.
Blood
; 126(17): 2005-15, 2015 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26361793
2.
TET1 plays an essential oncogenic role in MLL-rearranged leukemia.
Proc Natl Acad Sci U S A
; 110(29): 11994-9, 2013 Jul 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-23818607
3.
miR-9 is an essential oncogenic microRNA specifically overexpressed in mixed lineage leukemia-rearranged leukemia.
Proc Natl Acad Sci U S A
; 110(28): 11511-6, 2013 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-23798388
4.
PBX3 is an important cofactor of HOXA9 in leukemogenesis.
Blood
; 121(8): 1422-31, 2013 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-23264595
5.
MiR-495 is a tumor-suppressor microRNA down-regulated in MLL-rearranged leukemia.
Proc Natl Acad Sci U S A
; 109(47): 19397-402, 2012 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-23132946
6.
Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML.
Blood
; 119(10): 2314-24, 2012 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-22251480
7.
Aberrant overexpression and function of the miR-17-92 cluster in MLL-rearranged acute leukemia.
Proc Natl Acad Sci U S A
; 107(8): 3710-5, 2010 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-20133587
8.
Two isoforms of HOXA9 function differently but work synergistically in human MLL-rearranged leukemia.
Blood Cells Mol Dis
; 49(2): 102-6, 2012 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22633751
9.
Distinct microRNA expression profiles in acute myeloid leukemia with common translocations.
Proc Natl Acad Sci U S A
; 105(40): 15535-40, 2008 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-18832181
10.
MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia.
Proc Natl Acad Sci U S A
; 104(50): 19971-6, 2007 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-18056805
11.
Publisher Correction: miR-196b directly targets both HOXA9/MEIS1 oncogenes and FAS tumour suppressor in MLL-rearranged leukaemia.
Nat Commun
; 9: 16192, 2018 04 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29633759
12.
FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N6-Methyladenosine RNA Demethylase.
Cancer Cell
; 31(1): 127-141, 2017 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28017614
13.
Identification of MLL-fusion/MYCâ£miR-26â£TET1 signaling circuit in MLL-rearranged leukemia.
Cancer Lett
; 372(2): 157-65, 2016 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-26791235
14.
PBX3 and MEIS1 Cooperate in Hematopoietic Cells to Drive Acute Myeloid Leukemias Characterized by a Core Transcriptome of the MLL-Rearranged Disease.
Cancer Res
; 76(3): 619-29, 2016 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26747896
15.
Eradication of Acute Myeloid Leukemia with FLT3 Ligand-Targeted miR-150 Nanoparticles.
Cancer Res
; 76(15): 4470-80, 2016 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27280396
16.
miR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemia.
Nat Commun
; 7: 11452, 2016 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-27116251
17.
A t(11;15) fuses MLL to two different genes, AF15q14 and a novel gene MPFYVE on chromosome 15.
Oncogene
; 22(9): 1400-10, 2003 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-12618766
18.
Identification of a 24-gene prognostic signature that improves the European LeukemiaNet risk classification of acute myeloid leukemia: an international collaborative study.
J Clin Oncol
; 31(9): 1172-81, 2013 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-23382473
19.
Blockade of miR-150 maturation by MLL-fusion/MYC/LIN-28 is required for MLL-associated leukemia.
Cancer Cell
; 22(4): 524-35, 2012 Oct 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-23079661
20.
miR-196b directly targets both HOXA9/MEIS1 oncogenes and FAS tumour suppressor in MLL-rearranged leukaemia.
Nat Commun
; 3: 688, 2012 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22353710