Detalhe da pesquisa
1.
Epigenetic therapy inhibits metastases by disrupting premetastatic niches.
Nature
; 579(7798): 284-290, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32103175
2.
The genomic and evolutionary landscapes of anaplastic thyroid carcinoma.
Cell Rep
; 43(3): 113826, 2024 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38412093
3.
A Phase I Study of Dinaciclib in Combination With MK-2206 in Patients With Advanced Pancreatic Cancer.
Clin Transl Sci
; 13(6): 1178-1188, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32738099
4.
A Phase I Trial of the VEGF Receptor Tyrosine Kinase Inhibitor Pazopanib in Combination with the MEK Inhibitor Trametinib in Advanced Solid Tumors and Differentiated Thyroid Cancers.
Clin Cancer Res
; 25(18): 5475-5484, 2019 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31186313
5.
Cyclin-dependent kinase 5 activity controls cell motility and metastatic potential of prostate cancer cells.
Cancer Res
; 66(15): 7509-15, 2006 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16885348
6.
O-GlcNAcylation is required for mutant KRAS-induced lung tumorigenesis.
J Clin Invest
; 128(11): 4924-4937, 2018 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30130254
7.
Selective growth inhibition in BRAF mutant thyroid cancer by the mitogen-activated protein kinase kinase 1/2 inhibitor AZD6244.
J Clin Endocrinol Metab
; 92(12): 4712-8, 2007 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17878251
8.
The Ras/Raf/MEK/extracellular signal-regulated kinase pathway induces autocrine-paracrine growth inhibition via the leukemia inhibitory factor/JAK/STAT pathway.
Mol Cell Biol
; 23(2): 543-54, 2003 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-12509453
9.
Notch signaling induces rapid degradation of achaete-scute homolog 1.
Mol Cell Biol
; 22(9): 3129-39, 2002 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-11940670
10.
Recent advances in the biology and therapy of medullary thyroid carcinoma.
F1000Res
; 6: 2184, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29333262
11.
Activity of irinotecan and the tyrosine kinase inhibitor CEP-751 in medullary thyroid cancer.
J Clin Endocrinol Metab
; 91(1): 79-84, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16263812
12.
Epidermal growth factor receptor-independent constitutive activation of STAT3 in head and neck squamous cell carcinoma is mediated by the autocrine/paracrine stimulation of the interleukin 6/gp130 cytokine system.
Cancer Res
; 63(11): 2948-56, 2003 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12782602
13.
CEP-701 and CEP-751 inhibit constitutively activated RET tyrosine kinase activity and block medullary thyroid carcinoma cell growth.
Cancer Res
; 63(17): 5559-63, 2003 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-14500395
14.
Long-Term ERK Inhibition in KRAS-Mutant Pancreatic Cancer Is Associated with MYC Degradation and Senescence-like Growth Suppression.
Cancer Cell
; 29(1): 75-89, 2016 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26725216
15.
Regulation of neuroendocrine differentiation in gastrointestinal carcinoid tumor cells by notch signaling.
J Clin Endocrinol Metab
; 90(7): 4350-6, 2005 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-15870121
16.
Trametinib with and without pazopanib has potent preclinical activity in thyroid cancer.
Oncol Rep
; 34(5): 2319-24, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26324075
17.
Combined Inhibition of Cyclin-Dependent Kinases (Dinaciclib) and AKT (MK-2206) Blocks Pancreatic Tumor Growth and Metastases in Patient-Derived Xenograft Models.
Mol Cancer Ther
; 14(7): 1532-9, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25931518
18.
The homeobox gene BARX2 can modulate cisplatin sensitivity in human epithelial ovarian cancer.
Int J Oncol
; 21(5): 929-33, 2002 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-12370737
19.
Small-molecule screening of PC3 prostate cancer cells identifies tilorone dihydrochloride to selectively inhibit cell growth based on cyclin-dependent kinase 5 expression.
Oncol Rep
; 32(1): 419-24, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24841903
20.
Cabozantinib in progressive medullary thyroid cancer.
J Clin Oncol
; 31(29): 3639-46, 2013 Oct 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24002501