Detalhe da pesquisa
1.
Native and Denaturing MS Protein Deconvolution for Biopharma: Monoclonal Antibodies and Antibody-Drug Conjugates to Polydisperse Membrane Proteins and Beyond.
Anal Chem
; 91(15): 9472-9480, 2019 08 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31194911
2.
Use of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical Species.
Drug Metab Dispos
; 47(10): 1111-1121, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31387871
3.
Native-MS Analysis of Monoclonal Antibody Conjugates by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry.
Anal Chem
; 90(1): 745-751, 2018 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29193956
4.
Targeted Molecular Imaging of Cancer Cells Using MS2-Based (129)Xe NMR.
Bioconjug Chem
; 27(8): 1796-801, 2016 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27454679
5.
Biodistribution of Antibody-MS2 Viral Capsid Conjugates in Breast Cancer Models.
Mol Pharm
; 13(11): 3764-3772, 2016 11 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27611245
6.
Optimization and expansion of a site-selective N-methylpyridinium-4-carboxaldehyde-mediated transamination for bacterially expressed proteins.
J Am Chem Soc
; 137(3): 1123-9, 2015 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25486267
7.
Synthetically Modified Viral Capsids as Versatile Carriers for Use in Antibody-Based Cell Targeting.
Bioconjug Chem
; 26(8): 1590-6, 2015 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26076186
8.
Mild bioconjugation through the oxidative coupling of ortho-aminophenols and anilines with ferricyanide.
Angew Chem Int Ed Engl
; 53(4): 1057-61, 2014 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-24311449
9.
Site-specific protein transamination using N-methylpyridinium-4-carboxaldehyde.
J Am Chem Soc
; 135(45): 17223-9, 2013 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24191658
10.
High-Throughput Mass Spectrometry for Biopharma: A Universal Modality and Target Independent Analytical Method for Accurate Biomolecule Characterization.
J Am Soc Mass Spectrom
; 33(11): 2191-2198, 2022 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36206542
11.
GIPR antagonist antibodies conjugated to GLP-1 peptide are bispecific molecules that decrease weight in obese mice and monkeys.
Cell Rep Med
; 2(5): 100263, 2021 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34095876
12.
High Mass Analysis with a Fourier Transform Ion Cyclotron Resonance Mass Spectrometer: From Inorganic Salt Clusters to Antibody Conjugates and Beyond.
J Am Soc Mass Spectrom
; 31(5): 1155-1162, 2020 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32196330
13.
Mismatch repair proteins collaborate with methyltransferases in the repair of O(6)-methylguanine.
DNA Repair (Amst)
; 7(2): 170-6, 2008 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17951114
14.
Quantitative collision-induced unfolding differentiates model antibody-drug conjugates.
Protein Sci
; 28(3): 598-608, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30499138
15.
Quantification of siRNA-Antibody Conjugates in Biological Matrices by Triplex-Forming Oligonucleotide ELISA.
Nucleic Acid Ther
; 29(3): 161-166, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30801231
16.
Engineering NaV1.7 Inhibitory JzTx-V Peptides with a Potency and Basicity Profile Suitable for Antibody Conjugation To Enhance Pharmacokinetics.
ACS Chem Biol
; 14(4): 806-818, 2019 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30875193
17.
Antibody Modification of p-Aminophenylalanine-Containing Proteins.
Methods Mol Biol
; 1798: 195-201, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29868961
18.
Progress and challenges in the optimization of toxin peptides for development as pain therapeutics.
Curr Opin Chem Biol
; 38: 70-79, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28376346
19.
Synthesis, biophysical, and biological studies of wild-type and mutant psalmopeotoxins--anti-malarial cysteine knot peptides from Psalmopoeus cambridgei.
Peptides
; 31(4): 533-40, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20067814