Detalhe da pesquisa
1.
Development and validation of multiplex assays for mouse and human IgG and IgA to Neisseria gonorrhoeae antigens.
J Infect Dis
; 2024 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38526341
2.
Mutations in PBP2 from ceftriaxone-resistant Neisseria gonorrhoeae alter the dynamics of the ß3-ß4 loop to favor a low-affinity drug-binding state.
J Biol Chem
; 297(4): 101188, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34529975
3.
Mutations in penicillin-binding protein 2 from cephalosporin-resistant Neisseria gonorrhoeae hinder ceftriaxone acylation by restricting protein dynamics.
J Biol Chem
; 295(21): 7529-7543, 2020 05 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32253235
4.
Recognition of the ß-lactam carboxylate triggers acylation of Neisseria gonorrhoeae penicillin-binding protein 2.
J Biol Chem
; 294(38): 14020-14032, 2019 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31362987
5.
Properly folded and functional PorB from Neisseria gonorrhoeae inhibits dendritic cell stimulation of CD4+ T cell proliferation.
J Biol Chem
; 293(28): 11218-11229, 2018 07 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29752412
6.
Antimicrobial Resistance in Neisseria gonorrhoeae: Proceedings of the STAR Sexually Transmitted Infection-Clinical Trial Group Programmatic Meeting.
Sex Transm Dis
; 46(3): e18-e25, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30363025
7.
Alanine 501 Mutations in Penicillin-Binding Protein 2 from Neisseria gonorrhoeae: Structure, Mechanism, and Effects on Cephalosporin Resistance and Biological Fitness.
Biochemistry
; 56(8): 1140-1150, 2017 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28145684
8.
Synthesis and Kinetic Analysis of Two Conformationally Restricted Peptide Substrates of Escherichia coli Penicillin-Binding Protein 5.
Biochemistry
; 55(29): 4065-76, 2016 07 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-27420403
9.
Diffusion of antibiotics through the PilQ secretin in Neisseria gonorrhoeae occurs through the immature, sodium dodecyl sulfate-labile form.
J Bacteriol
; 197(8): 1308-21, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25605303
10.
Structural effect of the Asp345a insertion in penicillin-binding protein 2 from penicillin-resistant strains of Neisseria gonorrhoeae.
Biochemistry
; 53(48): 7596-603, 2014 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-25403720
11.
UTP is not a biased agonist at human P2Y(11) receptors.
Purinergic Signal
; 10(4): 581-5, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25015314
12.
Ureidopenicillins Are Potent Inhibitors of Penicillin-Binding Protein 2 from Multidrug-Resistant Neisseria gonorrhoeae H041.
ACS Infect Dis
; 10(4): 1298-1311, 2024 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38446051
13.
Apical targeting of the P2Y(4) receptor is directed by hydrophobic and basic residues in the cytoplasmic tail.
Am J Physiol Cell Physiol
; 304(3): C228-39, 2013 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23054062
14.
Identification of amino acids conferring high-level resistance to expanded-spectrum cephalosporins in the penA gene from Neisseria gonorrhoeae strain H041.
Antimicrob Agents Chemother
; 57(7): 3029-36, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23587946
15.
Is GPR17 a P2Y/leukotriene receptor? examination of uracil nucleotides, nucleotide sugars, and cysteinyl leukotrienes as agonists of GPR17.
J Pharmacol Exp Ther
; 347(1): 38-46, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23908386
16.
Commensal Neisseria species share immune suppressive mechanisms with Neisseria gonorrhoeae.
PLoS One
; 18(4): e0284062, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37027389
17.
Loss of P2Y1 receptor desensitization does not impact hemostasis or thrombosis despite increased platelet reactivity in vitro.
J Thromb Haemost
; 21(7): 1891-1902, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36958516
18.
Preclinical safety and efficacy characterization of an LpxC inhibitor against Gram-negative pathogens.
Sci Transl Med
; 15(708): eadf5668, 2023 08 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37556556
19.
A highly conserved interaction involving the middle residue of the SXN active-site motif is crucial for function of class B penicillin-binding proteins: mutational and computational analysis of PBP 2 from N. gonorrhoeae.
Biochemistry
; 51(13): 2775-84, 2012 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-22397678
20.
Charged residues in the C-terminus of the P2Y1 receptor constitute a basolateral-sorting signal.
J Cell Sci
; 123(Pt 14): 2512-20, 2010 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20592187