Detalhe da pesquisa
1.
TATDN2 resolution of R-loops is required for survival of BRCA1-mutant cancer cells.
Nucleic Acids Res
; 51(22): 12224-12241, 2023 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37953292
2.
Cellular Responses to Widespread DNA Replication Stress.
Int J Mol Sci
; 24(23)2023 Nov 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38069223
3.
Targeting Replication Stress Response Pathways to Enhance Genotoxic Chemo- and Radiotherapy.
Molecules
; 27(15)2022 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35897913
4.
Metnase Mediates Loading of Exonuclease 1 onto Single Strand Overhang DNA for End Resection at Stalled Replication Forks.
J Biol Chem
; 292(4): 1414-1425, 2017 01 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-27974460
5.
Endonuclease EEPD1 Is a Gatekeeper for Repair of Stressed Replication Forks.
J Biol Chem
; 292(7): 2795-2804, 2017 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28049724
6.
EEPD1 Rescues Stressed Replication Forks and Maintains Genome Stability by Promoting End Resection and Homologous Recombination Repair.
PLoS Genet
; 11(12): e1005675, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26684013
7.
The endonuclease EEPD1 mediates synthetic lethality in RAD52-depleted BRCA1 mutant breast cancer cells.
Breast Cancer Res
; 19(1): 122, 2017 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29145865
8.
The DDN catalytic motif is required for Metnase functions in non-homologous end joining (NHEJ) repair and replication restart.
J Biol Chem
; 289(15): 10930-10938, 2014 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-24573677
9.
PARP1 is required for chromosomal translocations.
Blood
; 121(21): 4359-65, 2013 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-23568489
10.
Distinct roles for DNA-PK, ATM and ATR in RPA phosphorylation and checkpoint activation in response to replication stress.
Nucleic Acids Res
; 40(21): 10780-94, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22977173
11.
Methylation of histone H3 lysine 36 enhances DNA repair by nonhomologous end-joining.
Proc Natl Acad Sci U S A
; 108(2): 540-5, 2011 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-21187428
12.
Synthetic lethality: exploiting the addiction of cancer to DNA repair.
Blood
; 117(23): 6074-82, 2011 Jun 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-21441464
13.
Roles of homologous recombination in response to ionizing radiation-induced DNA damage.
Int J Radiat Biol
; 99(6): 903-914, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-34283012
14.
EEPD1 promotes repair of oxidatively-stressed replication forks.
NAR Cancer
; 5(1): zcac044, 2023 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-36683914
15.
Metnase promotes restart and repair of stalled and collapsed replication forks.
Nucleic Acids Res
; 38(17): 5681-91, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20457750
16.
Nucleases and Co-Factors in DNA Replication Stress Responses.
DNA (Basel)
; 2(1): 68-85, 2022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-36203968
17.
Metnase and EEPD1: DNA Repair Functions and Potential Targets in Cancer Therapy.
Front Oncol
; 12: 808757, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35155245
18.
Recombinant cell-detecting RaDR-GFP in mice reveals an association between genomic instability and radiation-induced-thymic lymphoma.
Am J Cancer Res
; 12(2): 562-573, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35261787
19.
Metnase mediates chromosome decatenation in acute leukemia cells.
Blood
; 114(9): 1852-8, 2009 Aug 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-19458360
20.
Chromatin remodelling at a DNA double-strand break site in Saccharomyces cerevisiae.
Nature
; 438(7066): 379-83, 2005 Nov 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-16292314