Detalhe da pesquisa
1.
Significant impact of time-of-day variation on metformin pharmacokinetics.
Diabetologia
; 66(6): 1024-1034, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36930251
2.
Physiologically Based Pharmacokinetic Modeling of Rosuvastatin to Predict Transporter-Mediated Drug-Drug Interactions.
Pharm Res
; 38(10): 1645-1661, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-34664206
3.
Low-dose empagliflozin as adjunct-to-insulin therapy in type 1 diabetes: A valid modelling and simulation analysis to confirm efficacy.
Diabetes Obes Metab
; 22(3): 427-433, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31858718
4.
Physiologically Based Pharmacokinetic Models of Probenecid and Furosemide to Predict Transporter Mediated Drug-Drug Interactions.
Pharm Res
; 37(12): 250, 2020 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33237382
5.
A Model-Informed Drug Development (MIDD) Approach for a Low Dose of Empagliflozin in Patients with Type 1 Diabetes.
Pharmaceutics
; 13(4)2021 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33918261
6.
A Physiologically-Based Pharmacokinetic (PBPK) Model Network for the Prediction of CYP1A2 and CYP2C19 Drug-Drug-Gene Interactions with Fluvoxamine, Omeprazole, S-mephenytoin, Moclobemide, Tizanidine, Mexiletine, Ethinylestradiol, and Caffeine.
Pharmaceutics
; 12(12)2020 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33302490
7.
A Mechanistic, Enantioselective, Physiologically Based Pharmacokinetic Model of Verapamil and Norverapamil, Built and Evaluated for Drug-Drug Interaction Studies.
Pharmaceutics
; 12(6)2020 Jun 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32560124
8.
A Comprehensive Whole-Body Physiologically Based Pharmacokinetic Drug-Drug-Gene Interaction Model of Metformin and Cimetidine in Healthy Adults and Renally Impaired Individuals.
Clin Pharmacokinet
; 59(11): 1419-1431, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32449077
9.
Prediction of cytotoxic drug concentrations occurring on the day of autologous stem cell rescue during a high-dose chemotherapy regimen.
Int J Clin Pharmacol Ther
; 51(1): 38-40, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23259995
10.
Thrombocytopenia following high-dose chemotherapy with carboplatin, etoposide and thiotepa in patients with testicular germ cell cancer.
Int J Clin Pharmacol Ther
; 51(1): 74-6, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23260006
11.
Population Pharmacokinetic- Pharmacodynamic Analysis to Characterize the Effect of Empagliflozin on Renal Glucose Threshold in Patients With Type 1 Diabetes Mellitus.
J Clin Pharmacol
; 58(5): 640-649, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29251772
12.
Population Pharmacokinetics and Exposure-Response (Efficacy and Safety/Tolerability) of Empagliflozin in Patients with Type 2 Diabetes.
Diabetes Ther
; 7(3): 455-71, 2016 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-27312794
13.
Open Systems Pharmacology Community-An Open Access, Open Source, Open Science Approach to Modeling and Simulation in Pharmaceutical Sciences.
CPT Pharmacometrics Syst Pharmacol
; 8(12): 878-882, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31671256