Detalhe da pesquisa
1.
Oxidative stress accelerates intestinal tumorigenesis by enhancing 8-oxoguanine-mediated mutagenesis in MUTYH-deficient mice.
Genome Res
; 34(1): 47-56, 2024 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38290979
2.
Site-specific genotoxicity of rubiadin: localization and histopathological changes in the kidneys of rats.
Arch Toxicol
; 97(12): 3273-3283, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37794257
3.
The role of DNA polymerase ζ in benzo[a]pyrene-induced mutagenesis in the mouse lung.
Mutagenesis
; 36(2): 155-164, 2021 05 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-33544859
4.
Chromosome aberrations induced by the non-mutagenic carcinogen acetamide involve in rat hepatocarcinogenesis through micronucleus formation in hepatocytes.
Arch Toxicol
; 95(8): 2851-2865, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34160648
5.
Background data of 2-year-old male and female F344 gpt delta rats.
J Toxicol Pathol
; 34(1): 23-31, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-33627942
6.
In vivo positive mutagenicity of 1,4-dioxane and quantitative analysis of its mutagenicity and carcinogenicity in rats.
Arch Toxicol
; 92(10): 3207-3221, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30155721
7.
Impact of Ribonucleotide Backbone on Translesion Synthesis and Repair of 7,8-Dihydro-8-oxoguanine.
J Biol Chem
; 291(46): 24314-24323, 2016 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27660390
8.
DNA polymerase κ-dependent DNA synthesis at stalled replication forks is important for CHK1 activation.
EMBO J
; 32(15): 2172-85, 2013 Jul 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-23799366
9.
Phosphorylation of protein phosphatase 2A facilitated an early stage of chemical carcinogenesis.
Toxicol Appl Pharmacol
; 336: 75-83, 2017 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29054680
10.
Lack of genotoxic mechanisms in early-stage furan-induced hepatocellular tumorigenesis in gpt delta rats.
J Appl Toxicol
; 37(2): 142-149, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27143483
11.
Validation study of the combined repeated-dose toxicity and genotoxicity assay using gpt delta rats.
Cancer Sci
; 106(5): 529-41, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25683344
12.
Structural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo4.
EMBO J
; 29(12): 2059-69, 2010 Jun 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-20512114
13.
Absence of in vivo genotoxicity of 3-monochloropropane-1,2-diol and associated fatty acid esters in a 4-week comprehensive toxicity study using F344 gpt delta rats.
Mutagenesis
; 29(4): 295-302, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24831098
14.
Ochratoxin A induces DNA double-strand breaks and large deletion mutations in the carcinogenic target site of gpt delta rats.
Mutagenesis
; 29(1): 27-36, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24243707
15.
Combined application of comprehensive analysis for DNA modification and reporter gene mutation assay to evaluate kidneys of gpt delta rats given madder color or its constituents.
Anal Bioanal Chem
; 406(9-10): 2467-75, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24493334
16.
In vivo mutagenicity of arsenite in the livers of gpt delta transgenic mice.
Mutat Res Genet Toxicol Environ Mutagen
; 760: 42-7, 2014 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24333349
17.
Possible contribution of 8-hydroxydeoxyguanosine to gene mutations in the kidney DNA of gpt delta rats following potassium bromate treatment.
Mutat Res Genet Toxicol Environ Mutagen
; 894: 503729, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38432777
18.
Escherichia coli DNA polymerase III is responsible for the high level of spontaneous mutations in mutT strains.
Mol Microbiol
; 86(6): 1364-75, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23043439
19.
Miscoding properties of 8-chloro-2'-deoxyguanosine, a hypochlorous acid-induced DNA adduct, catalysed by human DNA polymerases.
Mutagenesis
; 28(1): 81-8, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23076070
20.
Oxidative DNA damage and in vivo mutagenicity caused by reactive oxygen species generated in the livers of p53-proficient or -deficient gpt delta mice treated with non-genotoxic hepatocarcinogens.
J Appl Toxicol
; 33(12): 1433-41, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22972318