Detalhe da pesquisa
1.
GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation.
Genes Dev
; 23(1): 24-36, 2009 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19136624
2.
Imaging guided trials of the angiogenesis inhibitor sunitinib in mouse models predict efficacy in pancreatic neuroendocrine but not ductal carcinoma.
Proc Natl Acad Sci U S A
; 108(49): E1275-84, 2011 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-22084065
3.
AMG 509 (Xaluritamig), an Anti-STEAP1 XmAb 2+1 T-cell Redirecting Immune Therapy with Avidity-Dependent Activity against Prostate Cancer.
Cancer Discov
; 14(1): 90-103, 2024 01 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37861452
4.
Cancer cell-intrinsic resistance to BiTE therapy is mediated by loss of CD58 costimulation and modulation of the extrinsic apoptotic pathway.
J Immunother Cancer
; 10(3)2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35296559
5.
Characterization of an Anti-CD70 Half-Life Extended Bispecific T-Cell Engager (HLE-BiTE) and Associated On-Target Toxicity in Cynomolgus Monkeys.
Toxicol Sci
; 189(1): 32-50, 2022 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35583313
6.
The PSMA-targeting Half-life Extended BiTE Therapy AMG 160 has Potent Antitumor Activity in Preclinical Models of Metastatic Castration-resistant Prostate Cancer.
Clin Cancer Res
; 27(10): 2928-2937, 2021 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33504551
7.
Immunotherapy combinations overcome resistance to bispecific T cell engager treatment in T cell-cold solid tumors.
Sci Transl Med
; 13(608)2021 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34433637
8.
Targeting Multiple Myeloma with AMG 424, a Novel Anti-CD38/CD3 Bispecific T-cell-recruiting Antibody Optimized for Cytotoxicity and Cytokine Release.
Clin Cancer Res
; 25(13): 3921-3933, 2019 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30918018
9.
Measurement of Cancer Cell Growth Heterogeneity through Lentiviral Barcoding Identifies Clonal Dominance as a Characteristic of In Vivo Tumor Engraftment.
PLoS One
; 8(6): e67316, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23840661
10.
Endoglin requirement for BMP9 signaling in endothelial cells reveals new mechanism of action for selective anti-endoglin antibodies.
PLoS One
; 7(12): e50920, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23300529
11.
Differential contribution to neuroendocrine tumorigenesis of parallel egfr signaling in cancer cells and pericytes.
Genes Cancer
; 1(2): 125-41, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20975924