Detalhe da pesquisa
1.
Cerebrospinal fluid, brain, and spinal cord levels of L-aspartate signal excitatory neurotransmission abnormalities in multiple sclerosis patients and experimental autoimmune encephalomyelitis mouse model.
J Neurochem
; 166(3): 534-546, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37332201
2.
Homeostasis of serine enantiomers is disrupted in the post-mortem caudate putamen and cerebrospinal fluid of living Parkinson's disease patients.
Neurobiol Dis
; 184: 106203, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37336364
3.
Perturbation of serine enantiomers homeostasis in the striatum of MPTP-lesioned monkeys and mice reflects the extent of dopaminergic midbrain degeneration.
Neurobiol Dis
; 184: 106226, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37451474
4.
Analysis of mRNA and Protein Levels of CAP2, DLG1 and ADAM10 Genes in Post-Mortem Brain of Schizophrenia, Parkinson's and Alzheimer's Disease Patients.
Int J Mol Sci
; 23(3)2022 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35163460
5.
Prenatal and Early Postnatal Cerebral d-Aspartate Depletion Influences l-Amino Acid Pathways, Bioenergetic processes, and Developmental Brain Metabolism.
J Proteome Res
; 20(1): 727-739, 2021 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33274941
6.
Cerebrospinal fluid levels of L-glutamate signal central inflammatory neurodegeneration in multiple sclerosis.
J Neurochem
; 159(5): 857-866, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34547109
7.
High performance liquid chromatography determination of L-glutamate, L-glutamine and glycine content in brain, cerebrospinal fluid and blood serum of patients affected by Alzheimer's disease.
Amino Acids
; 53(3): 435-449, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-33616735
8.
Prenatal expression of D-aspartate oxidase causes early cerebral D-aspartate depletion and influences brain morphology and cognitive functions at adulthood.
Amino Acids
; 52(4): 597-617, 2020 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-32185508
9.
New Evidence on the Role of D-Aspartate Metabolism in Regulating Brain and Endocrine System Physiology: From Preclinical Observations to Clinical Applications.
Int J Mol Sci
; 21(22)2020 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33218144
10.
Age-Related Changes in D-Aspartate Oxidase Promoter Methylation Control Extracellular D-Aspartate Levels and Prevent Precocious Cell Death during Brain Aging.
J Neurosci
; 36(10): 3064-78, 2016 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26961959
11.
Rhes regulates dopamine D2 receptor transmission in striatal cholinergic interneurons.
Neurobiol Dis
; 78: 146-61, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25818655
12.
Nusinersen mitigates neuroinflammation in severe spinal muscular atrophy patients.
Commun Med (Lond)
; 3(1): 28, 2023 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36792810
13.
SMN deficiency perturbs monoamine neurotransmitter metabolism in spinal muscular atrophy.
Commun Biol
; 6(1): 1155, 2023 11 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37957344
14.
Nusinersen Induces Disease-Severity-Specific Neurometabolic Effects in Spinal Muscular Atrophy.
Biomolecules
; 12(10)2022 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36291640
15.
Machine Learning algorithm unveils glutamatergic alterations in the post-mortem schizophrenia brain.
Schizophrenia (Heidelb)
; 8(1): 8, 2022 02 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35217646
16.
Abnormal RasGRP1 Expression in the Post-Mortem Brain and Blood Serum of Schizophrenia Patients.
Biomolecules
; 12(2)2022 02 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35204828
17.
D-aspartate oxidase gene duplication induces social recognition memory deficit in mice and intellectual disabilities in humans.
Transl Psychiatry
; 12(1): 305, 2022 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35915065
18.
Cerebrospinal fluid and serum d-serine concentrations are unaltered across the whole clinical spectrum of Alzheimer's disease.
Biochim Biophys Acta Proteins Proteom
; 1868(12): 140537, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32896673
19.
Dysfunctional d-aspartate metabolism in BTBR mouse model of idiopathic autism.
Biochim Biophys Acta Proteins Proteom
; 1868(12): 140531, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32853769
20.
RasGRP1 is a causal factor in the development of l-DOPA-induced dyskinesia in Parkinson's disease.
Sci Adv
; 6(18): eaaz7001, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32426479