Detalhe da pesquisa
1.
Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis.
Nature
; 616(7958): 755-763, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37046083
2.
A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies.
Nat Methods
; 19(12): 1599-1611, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36303018
3.
Whole genome sequence analysis of platelet traits in the NHLBI Trans-Omics for Precision Medicine (TOPMed) initiative.
Hum Mol Genet
; 31(3): 347-361, 2022 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34553764
4.
SLEMM: million-scale genomic predictions with window-based SNP weighting.
Bioinformatics
; 39(3)2023 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36897019
5.
Allele-specific variation at APOE increases nonalcoholic fatty liver disease and obesity but decreases risk of Alzheimer's disease and myocardial infarction.
Hum Mol Genet
; 30(15): 1443-1456, 2021 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33856023
6.
De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population.
Proc Natl Acad Sci U S A
; 117(5): 2560-2569, 2020 02 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31964835
7.
Impact of Rare and Common Genetic Variants on Diabetes Diagnosis by Hemoglobin A1c in Multi-Ancestry Cohorts: The Trans-Omics for Precision Medicine Program.
Am J Hum Genet
; 105(4): 706-718, 2019 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31564435
8.
Efficient Variant Set Mixed Model Association Tests for Continuous and Binary Traits in Large-Scale Whole-Genome Sequencing Studies.
Am J Hum Genet
; 104(2): 260-274, 2019 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30639324
9.
A fully adjusted two-stage procedure for rank-normalization in genetic association studies.
Genet Epidemiol
; 43(3): 263-275, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30653739
10.
Exome-chip meta-analysis identifies association between variation in ANKRD26 and platelet aggregation.
Platelets
; 30(2): 164-173, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-29185836
11.
Cattle Sex-Specific Recombination and Genetic Control from a Large Pedigree Analysis.
PLoS Genet
; 11(11): e1005387, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26540184
12.
Dissection of additive, dominance, and imprinting effects for production and reproduction traits in Holstein cattle.
BMC Genomics
; 18(1): 425, 2017 05 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-28558656
13.
Evidence for several independent genetic variants affecting lipoprotein (a) cholesterol levels.
Hum Mol Genet
; 24(8): 2390-400, 2015 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25575512
14.
Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response.
Pharmacogenet Genomics
; 27(4): 159-163, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28207573
15.
Null mutation in hormone-sensitive lipase gene and risk of type 2 diabetes.
N Engl J Med
; 370(24): 2307-2315, 2014 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24848981
16.
Selecting sequence variants to improve genomic predictions for dairy cattle.
Genet Sel Evol
; 49(1): 32, 2017 03 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28270096
17.
A central role for GRB10 in regulation of islet function in man.
PLoS Genet
; 10(4): e1004235, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24699409
18.
Genome-Wide Association Analysis of Young-Onset Stroke Identifies a Locus on Chromosome 10q25 Near HABP2.
Stroke
; 47(2): 307-16, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26732560
19.
The common genetic influence over processing speed and white matter microstructure: Evidence from the Old Order Amish and Human Connectome Projects.
Neuroimage
; 125: 189-197, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26499807
20.
Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations.
Hum Mol Genet
; 23(9): 2498-510, 2014 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24345515