Pesquisa | Biblioteca Virtual em Saúde

1.

Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection.

Hariharan, Vignesh N; Shin, Minwook; Chang, Ching-Wen; O'Reilly, Daniel; Biscans, Annabelle; Yamada, Ken; Guo, Zhiru; Somasundaran, Mohan; Tang, Qi; Monopoli, Kathryn; Krishnamurthy, Pranathi Meda; Devi, Gitali; McHugh, Nicholas; Cooper, David A; Echeverria, Dimas; Cruz, John; Chan, Io Long; Liu, Ping; Lim, Sun-Young; McConnell, Jill; Singh, Satya Prakash; Hildebrand, Samuel; Sousa, Jacquelyn; Davis, Sarah M; Kennedy, Zachary; Ferguson, Chantal; Godinho, Bruno M D C; Thillier, Yann; Caiazzi, Jillian; Ly, Socheata; Muhuri, Manish; Kelly, Karen; Humphries, Fiachra; Cousineau, Alyssa; Parsi, Krishna Mohan; Li, Qi; Wang, Yang; Maehr, René; Gao, Guangping; Korkin, Dmitry; McDougall, William M; Finberg, Robert W; Fitzgerald, Katherine A; Wang, Jennifer P; Watts, Jonathan K; Khvorova, Anastasia.

Proc Natl Acad Sci U S A ; 120(11): e2219523120, 2023 03 14.

Artigo em Inglês | MEDLINE | ID: mdl-36893269

2.

Markers of platelet activation foR identification of late onset sEpsis in infaNTs: PARENT study protocol.

O'Reilly, Daniel; Murphy, Claire Anne; Moore, Carmel Maria; Ní Áinle, Fionnuala; Gormley, Isobel Claire; Morrell, Craig N; Curley, Anna; Mc Callion, Naomi; Maguire, Patricia.

Pediatr Res ; 95(3): 852-856, 2024 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-37758864

3.

Di-valent siRNA-mediated silencing of MSH3 blocks somatic repeat expansion in mouse models of Huntington's disease.

O'Reilly, Daniel; Belgrad, Jillian; Ferguson, Chantal; Summers, Ashley; Sapp, Ellen; McHugh, Cassandra; Mathews, Ella; Boudi, Adel; Buchwald, Julianna; Ly, Socheata; Moreno, Dimas; Furgal, Raymond; Luu, Eric; Kennedy, Zachary; Hariharan, Vignesh; Monopoli, Kathryn; Yang, X William; Carroll, Jeffery; DiFiglia, Marian; Aronin, Neil; Khvorova, Anastasia.

Mol Ther ; 31(6): 1661-1674, 2023 06 07.

Artigo em Inglês | MEDLINE | ID: mdl-37177784

4.

Changes in inflammatory proteins following platelet transfusion in a neonatal population.

Moore, Carmel Maria; O'Reilly, Daniel; McCallion, Naomi; Curley, Anna E.

Pediatr Res ; 94(6): 1973-1977, 2023 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-37443343

5.

Entomological Surveillance Planning Tool (ESPT)-generated actionable evidence on human and vector behaviours optimizes present interventions and reduces exposure to Anopheles vectors in two communities of Guna Yala, Panamá.

Ávila, Mario I; Vajda, Élodie A; Jeffrey Gutiérrez, Eileen; Gibson, Daragh; Renteria, Mariela Mosquera; Presley, Nicolas; O'Reilly, Daniel; Tatarsky, Allison; Lobo, Neil F.

Malar J ; 22(1): 26, 2023 Jan 25.

Artigo em Inglês | MEDLINE | ID: mdl-36698147

6.

Platelets in pediatric and neonatal sepsis: novel mediators of the inflammatory cascade.

O'Reilly, Daniel; Murphy, Claire A; Drew, Richard; El-Khuffash, Afif; Maguire, Patricia B; Ainle, Fionnuala Ni; Mc Callion, Naomi.

Pediatr Res ; 91(2): 359-367, 2022 01.

Artigo em Inglês | MEDLINE | ID: mdl-34711945

7.

The role of the calibrated automated thrombogram in neonates: describing mechanisms of neonatal haemostasis and evaluating haemostatic drugs.

Murphy, Claire A; Neary, Elaine; O'Reilly, Daniel P; Cullivan, Sarah; El-Khuffash, Afif; NíAinle, Fionnuala; Maguire, Patricia B; McCallion, Naomi; Kevane, Barry.

Eur J Pediatr ; 181(1): 23-33, 2022 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-34283272

8.

Biochemical testing for inborn errors of metabolism: experience from a large tertiary neonatal centre.

Dunne, Esme; O'Reilly, Daniel; Murphy, Claire A; Howard, Caoimhe; Kelleher, Grainne; Suttie, Thomas; Boyle, Michael A; Brady, Jennifer J; Knerr, Ina; Khuffash, Afif El.

Eur J Pediatr ; 181(10): 3725-3732, 2022 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-35945291

9.

A review of the role of extracellular vesicles in neonatal physiology and pathology.

Murphy, Claire A; O'Reilly, Daniel P; Neary, Elaine; El-Khuffash, Afif; NíAinle, Fionnuala; McCallion, Naomi; Maguire, Patricia B.

Pediatr Res ; 90(2): 289-299, 2021 08.

Artigo em Inglês | MEDLINE | ID: mdl-33184501

10.

Anopheles drivers of persisting malaria transmission in Guna Yala, Panamá: an operational investigation.

Ávila, Mario I; Vajda, Élodie A; Gutiérrez, Eileen Jeffrey; Gibson, Daragh A; Renteria, Mariela Mosquera; Presley, Nicholas; O'Reilly, Daniel; Burton, Timothy A; Tatarsky, Allison; Lobo, Neil F.

Malar J ; 20(1): 443, 2021 Nov 24.

Artigo em Inglês | MEDLINE | ID: mdl-34819092

11.

Maple syrup urine disease: Clinical outcomes, metabolic control, and genotypes in a screened population after four decades of newborn bloodspot screening in the Republic of Ireland.

O'Reilly, Daniel; Crushell, Ellen; Hughes, Joanne; Ryan, Stephanie; Rogers, Yvonne; Borovickova, Ingrid; Mayne, Philip; Riordan, Michael; Awan, Atif; Carson, Kevin; Hunter, Kim; Lynch, Bryan; Shahwan, Amre; Rüfenacht, Véronique; Häberle, Johannes; Treacy, Eileen P; Monavari, Ahmad A; Knerr, Ina.

J Inherit Metab Dis ; 44(3): 639-655, 2021 05.

Artigo em Inglês | MEDLINE | ID: mdl-33300147

12.

Extensive CRISPR RNA modification reveals chemical compatibility and structure-activity relationships for Cas9 biochemical activity.

O'Reilly, Daniel; Kartje, Zachary J; Ageely, Eman A; Malek-Adamian, Elise; Habibian, Maryam; Schofield, Annabelle; Barkau, Christopher L; Rohilla, Kushal J; DeRossett, Lauren B; Weigle, Austin T; Damha, Masad J; Gagnon, Keith T.

Nucleic Acids Res ; 47(2): 546-558, 2019 01 25.

Artigo em Inglês | MEDLINE | ID: mdl-30517736

13.

Mechanochemical Synthesis of Short DNA Fragments.

Thorpe, James D; O'Reilly, Daniel; Friscic, Tomislav; Damha, Masad J.

Chemistry ; 26(41): 8857-8861, 2020 Jul 22.

Artigo em Inglês | MEDLINE | ID: mdl-32166818

14.

Use of anti-reflux medications in infants under 1 year of age: a retrospective drug utilization study using national prescription reimbursement data.

O'Reilly, Daniel; Conway, Robert; O'Connor, Lois; Fitzpatrick, Patrick.

Eur J Pediatr ; 179(12): 1963-1967, 2020 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-33051717

15.

Next-Generation Peptide Nucleic Acid Chimeras Exhibit High Affinity and Potent Gene Silencing.

Debacker, Alexandre J; Sharma, Vivek K; Meda Krishnamurthy, Pranathi; O'Reilly, Daniel; Greenhill, Rachel; Watts, Jonathan K.

Biochemistry ; 58(6): 582-589, 2019 02 12.

Artigo em Inglês | MEDLINE | ID: mdl-30520300

16.

ECI Biocommentary: Daniel O'Reilly.

O'Reilly, Daniel.

Pediatr Res ; 95(3): 600, 2024 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-37993642

17.

Di-valent siRNA-mediated silencing of MSH3 blocks somatic repeat expansion in mouse models of Huntington's disease.

O'Reilly, Daniel; Belgrad, Jillian; Ferguson, Chantal; Summers, Ashley; Sapp, Ellen; McHugh, Cassandra; Mathews, Ella; Boudi, Adel; Buchwald, Julianna; Ly, Socheata; Moreno, Dimas; Furgal, Raymond; Luu, Eric; Kennedy, Zachary; Hariharan, Vignesh; Monopoli, Kathryn; Yang, X William; Carroll, Jeffery; DiFiglia, Marian; Aronin, Neil; Khvorova, Anastasia.

Mol Ther ; 31(11): 3355-3356, 2023 Nov 01.

Artigo em Inglês | MEDLINE | ID: mdl-37751745

18.

Trends in specialized low-allergy infant formula dispensing in Ireland: 2016-2021.

O'Reilly, Daniel; Conway, Robert; Murphy, Claire A; Munblit, Daniel; Fitzpatrick, Patrick.

Clin Exp Allergy ; 53(3): 367-371, 2023 03.

Artigo em Inglês | MEDLINE | ID: mdl-36695212

19.

Exploring Atypical Fluorine-Hydrogen Bonds and Their Effects on Nucleoside Conformations.

O'Reilly, Daniel; Stein, Robin S; Patrascu, Mihai Burai; Jana, Sunit Kumar; Kurian, Jerry; Moitessier, Nicolas; Damha, Masad J.

Chemistry ; 24(61): 16432-16439, 2018 Nov 02.

Artigo em Inglês | MEDLINE | ID: mdl-30125398

20.

Activating frataxin expression by single-stranded siRNAs targeting the GAA repeat expansion.

Shen, Xiulong; Kilikevicius, Audrius; O'Reilly, Daniel; Prakash, Thazha P; Damha, Masad J; Rigo, Frank; Corey, David R.

Bioorg Med Chem Lett ; 28(17): 2850-2855, 2018 09 15.

Artigo em Inglês | MEDLINE | ID: mdl-30076049

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Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection.

Markers of platelet activation foR identification of late onset sEpsis in infaNTs: PARENT study protocol.

Di-valent siRNA-mediated silencing of MSH3 blocks somatic repeat expansion in mouse models of Huntington's disease.

Changes in inflammatory proteins following platelet transfusion in a neonatal population.

Entomological Surveillance Planning Tool (ESPT)-generated actionable evidence on human and vector behaviours optimizes present interventions and reduces exposure to Anopheles vectors in two communities of Guna Yala, Panamá.

Platelets in pediatric and neonatal sepsis: novel mediators of the inflammatory cascade.

The role of the calibrated automated thrombogram in neonates: describing mechanisms of neonatal haemostasis and evaluating haemostatic drugs.

Biochemical testing for inborn errors of metabolism: experience from a large tertiary neonatal centre.

A review of the role of extracellular vesicles in neonatal physiology and pathology.

Anopheles drivers of persisting malaria transmission in Guna Yala, Panamá: an operational investigation.

Maple syrup urine disease: Clinical outcomes, metabolic control, and genotypes in a screened population after four decades of newborn bloodspot screening in the Republic of Ireland.

Extensive CRISPR RNA modification reveals chemical compatibility and structure-activity relationships for Cas9 biochemical activity.

Mechanochemical Synthesis of Short DNA Fragments.

Use of anti-reflux medications in infants under 1 year of age: a retrospective drug utilization study using national prescription reimbursement data.

Next-Generation Peptide Nucleic Acid Chimeras Exhibit High Affinity and Potent Gene Silencing.

ECI Biocommentary: Daniel O'Reilly.

Di-valent siRNA-mediated silencing of MSH3 blocks somatic repeat expansion in mouse models of Huntington's disease.

Trends in specialized low-allergy infant formula dispensing in Ireland: 2016-2021.

Exploring Atypical Fluorine-Hydrogen Bonds and Their Effects on Nucleoside Conformations.

Activating frataxin expression by single-stranded siRNAs targeting the GAA repeat expansion.