Detalhe da pesquisa
1.
Interleukin-12/23 deficiency differentially affects pathology in male and female Alzheimer's disease-like mice.
EMBO Rep
; 21(3): e48530, 2020 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32003148
2.
CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice.
Brain
; 142(10): 3243-3264, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31504240
3.
PLCγ2 regulates TREM2 signalling and integrin-mediated adhesion and migration of human iPSC-derived macrophages.
Sci Rep
; 11(1): 19842, 2021 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34615897
4.
Replicative senescence dictates the emergence of disease-associated microglia and contributes to Aß pathology.
Cell Rep
; 35(10): 109228, 2021 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34107254
5.
TREM2 Alzheimer's variant R47H causes similar transcriptional dysregulation to knockout, yet only subtle functional phenotypes in human iPSC-derived macrophages.
Alzheimers Res Ther
; 12(1): 151, 2020 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33198789
6.
Inhibition of IL-34 Unveils Tissue-Selectivity and Is Sufficient to Reduce Microglial Proliferation in a Model of Chronic Neurodegeneration.
Front Immunol
; 11: 579000, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33162994
7.
The Role of Microglia in Prion Diseases: A Paradigm of Functional Diversity.
Front Aging Neurosci
; 9: 207, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28690540
8.
Inhibition of IL-12/IL-23 signaling reduces Alzheimer's disease-like pathology and cognitive decline.
Nat Med
; 18(12): 1812-9, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23178247