Detalhe da pesquisa
1.
Whole-Genome Sequencing to Evaluate the Resistance Landscape Following Antimalarial Treatment Failure With Fosmidomycin-Clindamycin.
J Infect Dis
; 214(7): 1085-91, 2016 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27443612
2.
A Novel Fluorescence Resonance Energy Transfer-Based Screen in High-Throughput Format To Identify Inhibitors of Malarial and Human Glucose Transporters.
Antimicrob Agents Chemother
; 60(12): 7407-7414, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27736766
3.
Cap-domain closure enables diverse substrate recognition by the C2-type haloacid dehalogenase-like sugar phosphatase Plasmodium falciparum HAD1.
Acta Crystallogr D Biol Crystallogr
; 71(Pt 9): 1824-34, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26327372
4.
Resistance to the antimicrobial agent fosmidomycin and an FR900098 prodrug through mutations in the deoxyxylulose phosphate reductoisomerase gene (dxr).
Antimicrob Agents Chemother
; 59(9): 5511-9, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26124156
5.
The Glucose Transporter PfHT1 Is an Antimalarial Target of the HIV Protease Inhibitor Lopinavir.
Antimicrob Agents Chemother
; 59(10): 6203-9, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26248369
6.
Isoprenoid biosynthesis in Plasmodium falciparum.
Eukaryot Cell
; 13(11): 1348-59, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25217461
7.
Isoprenoid biosynthesis inhibition disrupts Rab5 localization and food vacuolar integrity in Plasmodium falciparum.
Eukaryot Cell
; 12(2): 215-23, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23223036
8.
Structural studies and protein engineering of inositol phosphate multikinase.
J Biol Chem
; 287(42): 35360-35369, 2012 Oct 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-22896696
9.
A second target of the antimalarial and antibacterial agent fosmidomycin revealed by cellular metabolic profiling.
Biochemistry
; 50(17): 3570-7, 2011 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-21438569
10.
Five questions about non-mevalonate isoprenoid biosynthesis.
PLoS Pathog
; 7(12): e1002323, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22216001
11.
Inositol phosphate multikinase dependent transcriptional control.
Adv Biol Regul
; 64: 9-19, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28342784
12.
Structure-Activity Relationships of the MEPicides: N-Acyl and O-Linked Analogs of FR900098 as Inhibitors of Dxr from Mycobacterium tuberculosis and Yersinia pestis.
ACS Infect Dis
; 2(12): 923-935, 2016 12 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27676224
13.
Sweet Talk: Regulating Glucose Metabolism in Toxoplasma.
Cell Host Microbe
; 18(2): 142-3, 2015 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-26269950
14.
Determinants of Anemia and Hemoglobin Concentration in Haitian School-Aged Children.
Am J Trop Med Hyg
; 93(5): 1092-8, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26350448
15.
Malaria parasites produce volatile mosquito attractants.
mBio
; 6(2)2015 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-25805727
16.
Plasmodium IspD (2-C-Methyl-D-erythritol 4-Phosphate Cytidyltransferase), an Essential and Druggable Antimalarial Target.
ACS Infect Dis
; 1(4): 157-167, 2015 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26783558
17.
The triphenylethylenes, a novel class of antifungals.
mBio
; 5(3): e01126-14, 2014 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-24781746
18.
Isoprenoid metabolism in apicomplexan parasites.
Curr Clin Microbiol Rep
; 1(3-4): 37-50, 2014 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25893156
19.
A sugar phosphatase regulates the methylerythritol phosphate (MEP) pathway in malaria parasites.
Nat Commun
; 5: 4467, 2014 Jul 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-25058848
20.
Functional genetic analysis of the Plasmodium falciparum deoxyxylulose 5-phosphate reductoisomerase gene.
Mol Biochem Parasitol
; 170(2): 108-11, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20018214