Detalhe da pesquisa
1.
Control of Glucocorticoid Receptor Levels by PTEN Establishes a Failsafe Mechanism for Tumor Suppression.
Mol Cell
; 80(2): 279-295.e8, 2020 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33065020
2.
The mechanisms of class 1A PI3K and Wnt/ß-catenin coupled signaling in breast cancer.
Biochem Soc Trans
; 51(4): 1459-1472, 2023 08 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37471270
3.
PtdIns(3,4,5)P3-dependent Rac exchanger 1 (P-Rex1) promotes mammary tumor initiation and metastasis.
Proc Natl Acad Sci U S A
; 117(45): 28056-28067, 2020 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33097662
4.
Functional and Phenotypic Characterisations of Common Syngeneic Tumour Cell Lines as Estrogen Receptor-Positive Breast Cancer Models.
Int J Mol Sci
; 24(6)2023 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36982737
5.
AKT signaling promotes DNA damage accumulation and proliferation in polycystic kidney disease.
Hum Mol Genet
; 29(1): 31-48, 2020 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31625572
6.
ß-catenin ablation exacerbates polycystic kidney disease progression.
Hum Mol Genet
; 28(2): 230-244, 2019 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30265301
7.
PTEN and Other PtdIns(3,4,5)P3 Lipid Phosphatases in Breast Cancer.
Int J Mol Sci
; 21(23)2020 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33276499
8.
PtdIns(3,4,5)P3-dependent Rac Exchanger 1 (PREX1) Rac-Guanine Nucleotide Exchange Factor (GEF) Activity Promotes Breast Cancer Cell Proliferation and Tumor Growth via Activation of Extracellular Signal-regulated Kinase 1/2 (ERK1/2) Signaling.
J Biol Chem
; 291(33): 17258-70, 2016 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27358402
9.
P-Rex1 and P-Rex2 RacGEFs and cancer.
Biochem Soc Trans
; 45(4): 963-77, 2017 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28710285
10.
Inositol polyphosphate 4-phosphatase II (INPP4B) is associated with chemoresistance and poor outcome in AML.
Blood
; 125(18): 2815-24, 2015 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-25736313
11.
The Phosphatidylinositol (3,4,5)-Trisphosphate-dependent Rac Exchanger 1·Ras-related C3 Botulinum Toxin Substrate 1 (P-Rex1·Rac1) Complex Reveals the Basis of Rac1 Activation in Breast Cancer Cells.
J Biol Chem
; 290(34): 20827-20840, 2015 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26112412
12.
INPP4B is highly expressed in prostate intermediate cells and its loss of expression in prostate carcinoma predicts for recurrence and poor long term survival.
Prostate
; 75(1): 92-102, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25284366
13.
An ENU-induced mouse mutant of SHIP1 reveals a critical role of the stem cell isoform for suppression of macrophage activation.
Blood
; 117(20): 5362-71, 2011 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-21421839
14.
Inositol polyphosphate 4-phosphatase II regulates PI3K/Akt signaling and is lost in human basal-like breast cancers.
Proc Natl Acad Sci U S A
; 107(51): 22231-6, 2010 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-21127264
15.
Silencer of death domains (SODD) inhibits skeletal muscle and kidney enriched inositol 5-phosphatase (SKIP) and regulates phosphoinositide 3-kinase (PI3K)/Akt signaling to the actin cytoskeleton.
J Biol Chem
; 286(34): 29758-70, 2011 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-21712384
16.
Identification of a proline-rich inositol polyphosphate 5-phosphatase (PIPP)â¢collapsin response mediator protein 2 (CRMP2) complex that regulates neurite elongation.
J Biol Chem
; 286(26): 23407-18, 2011 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21550974
17.
The FDA-Approved Drug Pyrvinium Selectively Targets ER+ Breast Cancer Cells with High INPP4B Expression.
Cancers (Basel)
; 15(1)2022 Dec 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36612130
18.
A late endosome signaling hub that couples PI3Kα and WNT/ß-catenin signaling in breast cancer.
Mol Cell Oncol
; 8(4): 1954470, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34616876
19.
The INPP4B paradox: Like PTEN, but different.
Adv Biol Regul
; 82: 100817, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34216856
20.
INPP4B promotes PI3Kα-dependent late endosome formation and Wnt/ß-catenin signaling in breast cancer.
Nat Commun
; 12(1): 3140, 2021 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34035258