Detalhe da pesquisa
1.
Bosentan Alters Endo- and Exogenous Bile Salt Disposition in Sandwich-Cultured Human Hepatocytes.
J Pharmacol Exp Ther
; 379(1): 20-32, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34349015
2.
Safety Assessment of Compounds after In Vitro Metabolic Conversion Using Zebrafish Eleuthero Embryos.
Int J Mol Sci
; 20(7)2019 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30959884
3.
MRP2 Inhibition by HIV Protease Inhibitors in Rat and Human Hepatocytes: A Quantitative Confocal Microscopy Study.
Drug Metab Dispos
; 46(5): 697-703, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29523599
4.
Relationship between In Vivo CYP3A4 Activity, CYP3A5 Genotype, and Systemic Tacrolimus Metabolite/Parent Drug Ratio in Renal Transplant Recipients and Healthy Volunteers.
Drug Metab Dispos
; 46(11): 1507-1513, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30166405
5.
Omics-based responses induced by bosentan in human hepatoma HepaRG cell cultures.
Arch Toxicol
; 92(6): 1939-1952, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29761207
6.
Metabolism of the synthetic cannabinoid 5F-PY-PICA by human and rat hepatocytes and identification of biliary analytical targets by directional efflux in sandwich-cultured rat hepatocytes using UHPLC-HR-MS/MS.
J Pharm Biomed Anal
; 149: 296-307, 2018 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29128830
7.
Extra collagen overlay prolongs the differentiated phenotype in sandwich-cultured rat hepatocytes.
J Pharmacol Toxicol Methods
; 90: 31-38, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29079456
8.
On the Role of Illness Duration and Nutrient Restriction in Cholestatic Alterations that Occur During Critical Illness.
Shock
; 50(2): 187-198, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29076974
9.
Drug-induced cholestasis risk assessment in sandwich-cultured human hepatocytes.
Toxicol In Vitro
; 34: 179-186, 2016 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-27046439
10.
Primary Hepatocytes in Sandwich Culture.
Methods Mol Biol
; 1250: 175-88, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26272142
11.
Drug-induced cholestasis detection in cryopreserved rat hepatocytes in sandwich culture.
J Pharmacol Toxicol Methods
; 73: 63-71, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25828992