Detalhe da pesquisa
1.
Beneficial effects of physical exercise for ß-cell maintenance in a type 1 diabetes mellitus animal model.
Exp Physiol
; 106(7): 1482-1497, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33913203
2.
The non-canonical NF-κB pathway is induced by cytokines in pancreatic beta cells and contributes to cell death and proinflammatory responses in vitro.
Diabetologia
; 59(3): 512-21, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26634571
3.
The human pancreatic islet transcriptome: expression of candidate genes for type 1 diabetes and the impact of pro-inflammatory cytokines.
PLoS Genet
; 8(3): e1002552, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22412385
4.
Huntingtin-interacting protein 14 is a type 1 diabetes candidate protein regulating insulin secretion and beta-cell apoptosis.
Proc Natl Acad Sci U S A
; 108(37): E681-8, 2011 Sep 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-21705657
5.
STAT1 is a master regulator of pancreatic {beta}-cell apoptosis and islet inflammation.
J Biol Chem
; 286(2): 929-41, 2011 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-20980260
6.
MDA5 and PTPN2, two candidate genes for type 1 diabetes, modify pancreatic beta-cell responses to the viral by-product double-stranded RNA.
Hum Mol Genet
; 19(1): 135-46, 2010 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19825843
7.
p53 up-regulated modulator of apoptosis (PUMA) activation contributes to pancreatic beta-cell apoptosis induced by proinflammatory cytokines and endoplasmic reticulum stress.
J Biol Chem
; 285(26): 19910-20, 2010 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-20421300
8.
Lipotoxicity and ß-Cell Failure in Type 2 Diabetes: Oxidative Stress Linked to NADPH Oxidase and ER Stress.
Cells
; 10(12)2021 11 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34943836
9.
Early Cytokine-Induced Transient NOX2 Activity Is ER Stress-Dependent and Impacts ß-Cell Function and Survival.
Antioxidants (Basel)
; 10(8)2021 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34439552
10.
Transient NADPH oxidase 2-dependent H2O2 production drives early palmitate-induced lipotoxicity in pancreatic islets.
Free Radic Biol Med
; 162: 1-13, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33249137
11.
ARHGAP21 Acts as an Inhibitor of the Glucose-Stimulated Insulin Secretion Process.
Front Endocrinol (Lausanne)
; 11: 599165, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33324349
12.
Cell-permeable peptides induce dose- and length-dependent cytotoxic effects.
Biochim Biophys Acta
; 1768(9): 2222-34, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17626783
13.
Transcriptional regulation of the endoplasmic reticulum stress gene chop in pancreatic insulin-producing cells.
Diabetes
; 56(4): 1069-77, 2007 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-17395747
14.
Loss of PPAR gamma in immune cells impairs the ability of abscisic acid to improve insulin sensitivity by suppressing monocyte chemoattractant protein-1 expression and macrophage infiltration into white adipose tissue.
J Nutr Biochem
; 19(4): 216-28, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-17618105
15.
The non-canonical NF-κB pathway and its contribution to ß-cell failure in diabetes.
J Mol Endocrinol
; 61(2): F1-F6, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29728424
16.
Prolactin protects against cytokine-induced beta-cell death by NFκB and JNK inhibition.
J Mol Endocrinol
; 61(1): 25-36, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29632026
17.
Cytokine-induced proapoptotic gene expression in insulin-producing cells is related to rapid, sustained, and nonoscillatory nuclear factor-kappaB activation.
Mol Endocrinol
; 20(8): 1867-79, 2006 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16556731
18.
Cytokines downregulate the sarcoendoplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic beta-cells.
Diabetes
; 54(2): 452-61, 2005 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-15677503
19.
Endoplasmic reticulum stress and the unfolded protein response in pancreatic islet inflammation.
J Mol Endocrinol
; 57(1): R1-R17, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27067637
20.
A20 Inhibits ß-Cell Apoptosis by Multiple Mechanisms and Predicts Residual ß-Cell Function in Type 1 Diabetes.
Mol Endocrinol
; 30(1): 48-61, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26652732