Detalhe da pesquisa
1.
Pharmacological characterization of a novel liver X receptor agonist with partial LXRα activity and a favorable window in nonhuman primates.
J Pharmacol Exp Ther
; 352(2): 305-14, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25467132
2.
Liver X receptor (LXR) partial agonists: biaryl pyrazoles and imidazoles displaying a preference for LXRß.
Bioorg Med Chem Lett
; 25(2): 372-7, 2015 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25435151
3.
Discovery of Heteroaryl Urea Isosteres for Formyl Peptide Receptor 2 Agonists.
ACS Med Chem Lett
; 13(6): 943-948, 2022 Jun 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35707160
4.
Selective FPR2 Agonism Promotes a Proresolution Macrophage Phenotype and Improves Cardiac Structure-Function Post Myocardial Infarction.
JACC Basic Transl Sci
; 6(8): 676-689, 2021 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-34466754
5.
Discovery of BMS-986235/LAR-1219: A Potent Formyl Peptide Receptor 2 (FPR2) Selective Agonist for the Prevention of Heart Failure.
J Med Chem
; 63(17): 9003-9019, 2020 09 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32407089
6.
Preservation of Post-Infarction Cardiac Structure and Function via Long-Term Oral Formyl Peptide Receptor Agonist Treatment.
JACC Basic Transl Sci
; 4(8): 905-920, 2019 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-31909300
7.
Pharmacological and x-ray structural characterization of a novel selective androgen receptor modulator: potent hyperanabolic stimulation of skeletal muscle with hypostimulation of prostate in rats.
Endocrinology
; 148(1): 4-12, 2007 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-17008401
8.
Discovery of potent and muscle selective androgen receptor modulators through scaffold modifications.
J Med Chem
; 50(13): 3015-25, 2007 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-17552509
9.
Discovery of potent, orally-active, and muscle-selective androgen receptor modulators based on an N-aryl-hydroxybicyclohydantoin scaffold.
J Med Chem
; 49(26): 7596-9, 2006 Dec 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-17181141
10.
Discovery of Highly Potent Liver X Receptor ß Agonists.
ACS Med Chem Lett
; 7(12): 1207-1212, 2016 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27994765
11.
Beneficial and Adverse Effects of an LXR Agonist on Human Lipid and Lipoprotein Metabolism and Circulating Neutrophils.
Cell Metab
; 24(2): 223-33, 2016 08 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27508871
12.
Selective retinoic acid receptor ligands for rheumatoid arthritis.
Curr Opin Investig Drugs
; 5(11): 1153-7, 2004 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-15573865
13.
Amorphous iridium complexes for electrophosphorescent light emitting devices.
Chem Commun (Camb)
; (7): 784-5, 2002 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-12119722
14.
11ß-hydroxysteroid dehydrogenase type 1 gene knockout attenuates atherosclerosis and in vivo foam cell formation in hyperlipidemic apoEâ»/â» mice.
PLoS One
; 8(2): e53192, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23383297
15.
N-aryl-oxazolidin-2-imine muscle selective androgen receptor modulators enhance potency through pharmacophore reorientation.
J Med Chem
; 52(9): 2794-8, 2009 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-19351168
16.
Synthesis and SAR of tetrahydropyrrolo[1,2-b][1,2,5]thiadiazol-2(3H)-one 1,1-dioxide analogues as highly potent selective androgen receptor modulators.
Bioorg Med Chem Lett
; 17(16): 4487-90, 2007 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17574413
17.
Tandem optimization of target activity and elimination of mutagenic potential in a potent series of N-aryl bicyclic hydantoin-based selective androgen receptor modulators.
Bioorg Med Chem Lett
; 17(7): 1860-4, 2007 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17292608
18.
Nuclear trafficking of FGFR1: a role for the transmembrane domain.
J Cell Biochem
; 88(6): 1273-91, 2003 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12647309
19.
Coherent effects in energy transport in model dendritic structures investigated by ultrafast fluorescence anisotropy spectroscopy.
J Am Chem Soc
; 124(8): 1736-43, 2002 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-11853451
20.
Inhibition of disease progression by a novel retinoid antagonist in animal models of arthritis.
J Rheumatol
; 30(2): 355-63, 2003 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-12563696