1.
RSC Adv
; 12(8): 4635-4639, 2022 Feb 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35425482
RESUMO
The asymmetric total synthesis of four lignans, dimethylmatairesinol, matairesinol, (-)-niranthin, and (+)-niranthin has been achieved using reductive ring-opening of cyclopropanes. Moreover, we performed bioassays of the synthesized (+)- and (-)-niranthins using hepatitis B and influenza viruses, which revealed the relationship between the enantiomeric structure and the anti-viral activity of niranthin.