Detalhe da pesquisa
1.
(2S,4S)-5-Fluoroleucine, (2S,4R)-5-Fluoroleucine, and 5,5'-Difluoroleucine in Escherichia coli PpiB: Protein Production, 19F NMR, and Ligand Sensing Enhanced by the γ-Gauche Effect.
Biochemistry
; 63(11): 1376-1387, 2024 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38753308
2.
Conformational Preferences of the Non-Canonical Amino Acids (2S,4S)-5-Fluoroleucine, (2S,4R)-5-Fluoroleucine, and 5,5'-Difluoroleucine in a Protein.
Biochemistry
; 63(11): 1388-1394, 2024 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38742763
3.
Genetic Encoding of Fluoro-l-tryptophans for Site-Specific Detection of Conformational Heterogeneity in Proteins by NMR Spectroscopy.
J Am Chem Soc
; 146(19): 13641-13650, 2024 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38687675
4.
Paramagnetic Chemical Probes for Studying Biological Macromolecules.
Chem Rev
; 122(10): 9571-9642, 2022 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35084831
5.
Electrostatic Contribution to 19F Chemical Shifts in Fluorotryptophans in Proteins.
Biochemistry
; 62(22): 3255-3264, 2023 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37934875
6.
Improved spectral resolution of [13C,1H]-HSQC spectra of aromatic amino acid residues in proteins produced by cell-free synthesis from inexpensive 13C-labelled precursors.
J Biomol NMR
; 77(4): 183-190, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37338652
7.
Main protease mutants of SARS-CoV-2 variants remain susceptible to nirmatrelvir.
Bioorg Med Chem Lett
; 62: 128629, 2022 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35182772
8.
Synthesis of fluorinated leucines, valines and alanines for use in protein NMR.
Org Biomol Chem
; 20(12): 2424-2432, 2022 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35262139
9.
Short-range ENDOR distance measurements between Gd(III) and trifluoromethyl labels in proteins.
Phys Chem Chem Phys
; 24(41): 25214-25226, 2022 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36222074
10.
Genetic Encoding of Cyanopyridylalanine for In-Cell Protein Macrocyclization by the Nitrile-Aminothiol Click Reaction.
Angew Chem Int Ed Engl
; 61(13): e202114154, 2022 03 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35102680
11.
Genetic Encoding of N6-(((Trimethylsilyl)methoxy)carbonyl)-l-lysine for NMR Studies of Protein-Protein and Protein-Ligand Interactions.
J Am Chem Soc
; 143(2): 1133-1143, 2021 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33399460
12.
Through-Space Scalar 19F-19F Couplings between Fluorinated Noncanonical Amino Acids for the Detection of Specific Contacts in Proteins.
J Am Chem Soc
; 143(46): 19587-19598, 2021 11 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34780162
13.
Cell-Free Synthesis of Selenoproteins in High Yield and Purity for Selective Protein Tagging.
Chembiochem
; 22(8): 1480-1486, 2021 04 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33319405
14.
A Chiral Lanthanide Tag for Stable and Rigid Attachment to Single Cysteine Residues in Proteins for NMR, EPR and Time-Resolved Luminescence Studies.
Chemistry
; 27(51): 13009-13023, 2021 Sep 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34152643
15.
Challenges of short substrate analogues as SARS-CoV-2 main protease inhibitors.
Bioorg Med Chem Lett
; 50: 128333, 2021 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34418570
16.
Synthesis of 13C/19F/2H labeled indoles for use as tryptophan precursors for protein NMR spectroscopy.
Org Biomol Chem
; 19(23): 5133-5147, 2021 06 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34032255
17.
Genetic Encoding of para-Pentafluorosulfanyl Phenylalanine: A Highly Hydrophobic and Strongly Electronegative Group for Stable Protein Interactions.
J Am Chem Soc
; 142(41): 17277-17281, 2020 10 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32975937
18.
Cell-free expression of natively folded hydrophobins.
Protein Expr Purif
; 170: 105591, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32032769
19.
Three-Dimensional Protein Structure Determination Using Pseudocontact Shifts of Backbone Amide Protons Generated by Double-Histidine Co2+-Binding Motifs at Multiple Sites.
Biochemistry
; 58(30): 3243-3250, 2019 07 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31282649
20.
Correction to "Electrostatic Contribution to 19F Chemical Shifts in Fluorotryptophans in Proteins".
Biochemistry
; 63(3): 367, 2024 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38241226