Detalhe da pesquisa
1.
Evolution of the clinical-stage hyperactive TcBuster transposase as a platform for robust non-viral production of adoptive cellular therapies.
Mol Ther
; 32(6): 1817-1834, 2024 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38627969
2.
Concurrent transposon engineering and CRISPR/Cas9 genome editing of primary CLL-1 chimeric antigen receptor-natural killer cells.
Cytotherapy
; 24(11): 1087-1094, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36050244
3.
Skeletal overgrowth-causing mutations mimic an allosterically activated conformation of guanylyl cyclase-B that is inhibited by 2,4,6,-trinitrophenyl ATP.
J Biol Chem
; 292(24): 10220-10229, 2017 06 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28450398
4.
A Glutamate-Substituted Mutant Mimics the Phosphorylated and Active Form of Guanylyl Cyclase-A.
Mol Pharmacol
; 92(1): 67-74, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28416574
5.
Catalytically Active Guanylyl Cyclase B Requires Endoplasmic Reticulum-mediated Glycosylation, and Mutations That Inhibit This Process Cause Dwarfism.
J Biol Chem
; 291(21): 11385-93, 2016 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-26980729
6.
Vicinal glutamates are better phosphomimetics: Phosphorylation is required for allosteric activation of guanylyl cyclase-A.
Front Mol Neurosci
; 15: 1012784, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36407758
7.
GABARAPs and LC3s have opposite roles in regulating ULK1 for autophagy induction.
Autophagy
; 16(4): 600-614, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31208283
8.
ULK1 phosphorylates Ser30 of BECN1 in association with ATG14 to stimulate autophagy induction.
Autophagy
; 14(4): 584-597, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29313410
9.
The ULK1 complex mediates MTORC1 signaling to the autophagy initiation machinery via binding and phosphorylating ATG14.
Autophagy
; 12(3): 547-64, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27046250
10.
ULK1 inhibits the kinase activity of mTORC1 and cell proliferation.
Autophagy
; 7(10): 1212-21, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21795849
11.
mTOR regulation of autophagy.
FEBS Lett
; 584(7): 1287-95, 2010 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-20083114
12.
ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery.
Mol Biol Cell
; 20(7): 1992-2003, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19225151