Detalhe da pesquisa
1.
Mechanisms of toxicity associated with six tyrosine kinase inhibitors in human hepatocyte cell lines.
J Appl Toxicol
; 38(3): 418-431, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29072336
2.
Mechanisms of hepatotoxicity associated with the monocyclic ß-lactam antibiotic BAL30072.
Arch Toxicol
; 91(11): 3647-3662, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28536862
3.
Mitochondrial oxidative stress plays a critical role in the cardiotoxicity of sunitinib: Running title: Sunitinib and oxidative stress in hearts.
Toxicology
; 426: 152281, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31445075
4.
Sunitinib induces hepatocyte mitochondrial damage and apoptosis in mice.
Toxicology
; 409: 13-23, 2018 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30031043
5.
Mechanisms of mitochondrial toxicity of the kinase inhibitors ponatinib, regorafenib and sorafenib in human hepatic HepG2 cells.
Toxicology
; 395: 34-44, 2018 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29341879
6.
Induction of mitophagy in the HEI-OC1 auditory cell line and activation of the Atg12/LC3 pathway in the organ of Corti.
Hear Res
; 361: 52-65, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29352609
7.
Prediction of Safety Margin and Optimization of Dosing Protocol for a Novel Antibiotic using Quantitative Systems Pharmacology Modeling.
Clin Transl Sci
; 11(5): 498-505, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29877622
8.
Hepatocellular Toxicity Associated with Tyrosine Kinase Inhibitors: Mitochondrial Damage and Inhibition of Glycolysis.
Front Pharmacol
; 8: 367, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28659801
9.
Kinetics of lipid bilayer permeation of a series of ionisable drugs and their correlation with human transporter-independent intestinal permeability.
Eur J Pharm Sci
; 104: 150-161, 2017 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28366650
10.
Mechanistic insights into selective killing of OXPHOS-dependent cancer cells by arctigenin.
Toxicol In Vitro
; 40: 55-65, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-27923774
11.
A liposomal fluorescence assay to study permeation kinetics of drug-like weak bases across the lipid bilayer.
J Control Release
; 173: 102-9, 2014 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24211703