Detalhe da pesquisa
1.
Loss of nuclear DNA ligase III reverts PARP inhibitor resistance in BRCA1/53BP1 double-deficient cells by exposing ssDNA gaps.
Mol Cell
; 81(22): 4692-4708.e9, 2021 11 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34555355
2.
Multi-omics analysis reveals distinct non-reversion mechanisms of PARPi resistance in BRCA1- versus BRCA2-deficient mammary tumors.
Cell Rep
; 42(5): 112538, 2023 05 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37209095
3.
Functional genetic dropout screens and in vivo validation of candidate therapeutic targets using mouse mammary tumoroids.
STAR Protoc
; 3(1): 101132, 2022 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35146447
4.
Filling in the gaps in PARP inhibitor-induced synthetic lethality.
Mol Cell Oncol
; 8(6): 2010512, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-35419484
5.
SMARCAD1-mediated active replication fork stability maintains genome integrity.
Sci Adv
; 7(19)2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33952518