Detalhe da pesquisa
1.
Treatment of type 2 diabetes with the designer cytokine IC7Fc.
Nature
; 574(7776): 63-68, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31554967
2.
ACAD10 is not required for metformin's metabolic actions or for maintenance of whole-body metabolism in C57BL/6J mice.
Diabetes Obes Metab
; 26(5): 1731-1745, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38351663
3.
Active Akt signaling triggers CLL toward Richter transformation via overactivation of Notch1.
Blood
; 137(5): 646-660, 2021 02 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33538798
4.
CRISPR base editing applications for identifying cancer-driving mutations.
Biochem Soc Trans
; 49(1): 269-280, 2021 02 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33449100
5.
Adipocyte-specific deletion of IL-6 does not attenuate obesity-induced weight gain or glucose intolerance in mice.
Am J Physiol Endocrinol Metab
; 317(4): E597-E604, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31386565
6.
The roles of c-Jun NH2-terminal kinases (JNKs) in obesity and insulin resistance.
J Physiol
; 594(2): 267-79, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26608096
7.
From cytokine to myokine: the emerging role of interleukin-6 in metabolic regulation.
Immunol Cell Biol
; 92(4): 331-9, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24751614
8.
Contraction-induced interleukin-6 gene transcription in skeletal muscle is regulated by c-Jun terminal kinase/activator protein-1.
J Biol Chem
; 287(14): 10771-9, 2012 Mar 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-22351769
9.
Hypothalamic and pituitary c-Jun N-terminal kinase 1 signaling coordinately regulates glucose metabolism.
Proc Natl Acad Sci U S A
; 107(13): 6028-33, 2010 Mar 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-20231445
10.
Deletion of the transcriptional regulator TFAP4 accelerates c-MYC-driven lymphomagenesis.
Cell Death Differ
; 30(6): 1447-1456, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36894688
11.
Case Study: CRISPR 101 - a novel online learning course harnessing innovative ways to teach a complex biomolecular technology.
Essays Biochem
; 66(1): 11-18, 2022 04 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35416243
12.
Generation of a CRISPR activation mouse that enables modelling of aggressive lymphoma and interrogation of venetoclax resistance.
Nat Commun
; 13(1): 4739, 2022 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35961968
13.
LXR stimulates a metabolic switch and reveals cholesterol homeostasis as a statin target in Tasmanian devil facial tumor disease.
Cell Rep
; 34(11): 108851, 2021 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33730574
14.
TRIM17 and TRIM28 antagonistically regulate the ubiquitination and anti-apoptotic activity of BCL2A1.
Cell Death Differ
; 26(5): 902-917, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30042493
15.
Author Correction: Generation of a CRISPR activation mouse that enables modelling of aggressive lymphoma and interrogation of venetoclax resistance.
Nat Commun
; 13(1): 5007, 2022 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36008403
16.
Mosaic Deficiency in Mitochondrial Oxidative Metabolism Promotes Cardiac Arrhythmia during Aging.
Cell Metab
; 21(5): 667-77, 2015 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25955204
17.
Distinct Roles for JNK and IKK Activation in Agouti-Related Peptide Neurons in the Development of Obesity and Insulin Resistance.
Cell Rep
; 9(4): 1495-506, 2014 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25456138
18.
Alteration of JNK-1 signaling in skeletal muscle fails to affect glucose homeostasis and obesity-associated insulin resistance in mice.
PLoS One
; 8(1): e54247, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23349837
19.
An update on using CRISPR/Cas9 in the one-cell stage mouse embryo for generating complex mutant alleles.
Cell Death Differ
; 24(10): 1821-1822, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28753205
20.
Loss of Roquin induces early death and immune deregulation but not autoimmunity.
J Exp Med
; 208(9): 1749-56, 2011 Aug 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-21844204