Detalhe da pesquisa
1.
Designed P-glycoprotein inhibitors with triazol-tetrahydroisoquinoline-core increase doxorubicin-induced mortality in multidrug resistant K562/A02 cells.
Bioorg Med Chem
; 27(15): 3347-3357, 2019 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31202598
2.
Pro-apoptotic cationic host defense peptides rich in lysine or arginine to reverse drug resistance by disrupting tumor cell membrane.
Amino Acids
; 49(9): 1601-1610, 2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28664269
3.
Synthesis and biological evaluation of JL-A7 derivatives as potent ABCB1 inhibitors.
Bioorg Med Chem
; 25(15): 4194-4202, 2017 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28645831
4.
Design, synthesis and biological evaluation of novel analgesic agents targeting both cyclooxygenase and TRPV1.
Bioorg Med Chem
; 24(4): 849-57, 2016 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26795113
5.
Design, synthesis and biological evaluation of LBM-A5 derivatives as potent P-glycoprotein-mediated multidrug resistance inhibitors.
Bioorg Med Chem
; 24(10): 2287-97, 2016 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27073052
6.
Discovery of novel pyrrole-based scaffold as potent and orally bioavailable free fatty acid receptor 1 agonists for the treatment of type 2 diabetes.
Bioorg Med Chem
; 24(9): 1981-7, 2016 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27020683
7.
A bioinspired approach to fabricate fluorescent nanotubes with strong water adhesion by soft template electropolymerization and post-grafting.
J Colloid Interface Sci
; 606(Pt 1): 236-247, 2022 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34390991
8.
Design, synthesis, and biological evaluation of novel nitric oxide releasing dehydroandrographolide derivatives.
Chin J Nat Med
; 16(10): 782-790, 2018 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-30322612
9.
Injectable self-assembled peptide hydrogels for glucose-mediated insulin delivery.
Biomater Sci
; 6(6): 1480-1491, 2018 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-29623975
10.
Exploration of 2-((Pyridin-4-ylmethyl)amino)nicotinamide Derivatives as Potent Reversal Agents against P-Glycoprotein-Mediated Multidrug Resistance.
J Med Chem
; 60(7): 2930-2943, 2017 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-28301155
11.
A novel mitochondria-targeting fluorescent probe for hydrogen sulfide in living cells.
Chem Biol Drug Des
; 90(2): 167-174, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28109134
12.
Discovery of phenylsulfonyl acetic acid derivatives with improved efficacy and safety as potent free fatty acid receptor 1 agonists for the treatment of type 2 diabetes.
Eur J Med Chem
; 138: 458-479, 2017 Sep 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-28689096
13.
Design, Synthesis, and Pharmacological Characterization of N-(4-(2 (6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)yl)ethyl)phenyl)quinazolin-4-amine Derivatives: Novel Inhibitors Reversing P-Glycoprotein-Mediated Multidrug Resistance.
J Med Chem
; 60(8): 3289-3302, 2017 04 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28355069
14.
Synthesis of Analogues of BCTC Incorporating a Pyrrolidinyl Linker and Biological Evaluation as Transient Receptor Potential Vanilloid 1 Antagonists.
Chem Biol Drug Des
; 87(2): 306-11, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26360809
15.
Design, synthesis and Structure-activity relationship studies of new thiazole-based free fatty acid receptor 1 agonists for the treatment of type 2 diabetes.
Eur J Med Chem
; 113: 246-57, 2016 May 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26945112