[Mechanism of the effect of phytohemagglutinin as a stimulator of wound healing]. / K mekhanizmu deistviia fitogemaggliutinina kak stimuliatora zazhivleniia ran.

Phytohemagglutinin (PHA) produced by Difco, USA, (3.3 microgram per 1 mg of unguentum base) was tested as a stimulator of the healing of suppurative skin-muscle wounds 4 cm2 in area in 70 rabbits divided into 3 groups according to reaction to the intracutaneous test with PHA. Enhanced wound healing was observed only in poorly reacting rabbits (20.7 against 31.1 days in control). A considerable increase in the number of activated lymphocytes and cells of monocyte-macrophage group in the wound exudate, increased phagocytosis as well as more rapid and intensive development of proliferative processes were also established. The stimulation mechanism includes the direct PHA effect on inflammation cells and epithelium and a complex chain of both direct and mediated cellular interactions.

[Vitamin E and its structural analogs in tuberculosis]. / Vitamin E i ego strukturnye analogi pri tuberkuleze.

Efficiency of tocopherol, its analog with a shortened side chain as well as their quinons for tuberculosis was determined. All the studied compounds inhibited peroxide-formation processes in the liver homogenate and mitochondria. The vitamin E amount in the blood is considerably decreased in case of tuberculosis. The studied analogs increased its content and possessed a weak tuberculostatic but expressed antiedemic and antiinflammatory action. Administration of vitamin E in combination with isoniazid to sick animals had a favourable effect on the processes of tissue respiration and oxidative phosphorylation. If taking a sum of characters, tocopherol acetate with a shortened side chain is the most efficient of all the analogs under study for the tuberculosis therapy.

[Improvement of differential diagnosis of tuberculosis and cancer of the lungs based on a mathematical method]. / Optimizatsiia differentsial'noi diagnostiki tuberkuleza i raka legkikh na osnove matematicheskogo metoda.

A table differential diagnosis algorithm has been developed to improve the diagnosis of tuberculosis and lung cancer in tuberculosis institutions. The algorithm proved effective already at the stage of primary antituberculosis aid, being a reliable tool in the diagnosis of lung cancer and tuberculosis, contributing to shorter examinations of patients, earlier administration of adequate treatment.

[The characteristics of treating patients with chronic obstructive bronchitis combined with chronic pancreatitis and biliary dyskinesia]. / Osobennosti lecheniia bol'nykh khronicheskim obstruktivnym bronkhitom v sochetanii s khronicheskim pankreatitom i diskineziei zhelchevyvodiashchikh putei.

It was established that patients with chronic obstructive bronchitis widely suffered of chronic pancreatitis, diffuse pancreatofibrosis, hypertensive types of disorders of the main sphincters of the biliary system. It was found that solizyme increases the efficacy of complex therapy of the patients with chronic obstructive bronchitis in the presence of diffuse pancreatofibrosis. This improves the indices of bronchial patency and reduces allergization of the body.