Detalhe da pesquisa
1.
Rare variant associations with plasma protein levels in the UK Biobank.
Nature
; 622(7982): 339-347, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37794183
2.
Intramuscular AZD7442 (Tixagevimab-Cilgavimab) for Prevention of Covid-19.
N Engl J Med
; 386(23): 2188-2200, 2022 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35443106
3.
Phase 3 Safety and Efficacy of AZD1222 (ChAdOx1 nCoV-19) Covid-19 Vaccine.
N Engl J Med
; 385(25): 2348-2360, 2021 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34587382
4.
Direct intramyocardial injection of VEGF mRNA in patients undergoing coronary artery bypass grafting.
Mol Ther
; 31(3): 866-874, 2023 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36528793
5.
AZD7442 (Tixagevimab/Cilgavimab) for Post-Exposure Prophylaxis of Symptomatic Coronavirus Disease 2019.
Clin Infect Dis
; 76(7): 1247-1256, 2023 04 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36411267
6.
Direct Interaction of PP2A Phosphatase with GABAB Receptors Alters Functional Signaling.
J Neurosci
; 40(14): 2808-2816, 2020 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32111696
7.
Estradiol modulates the efficacy of synaptic inhibition by decreasing the dwell time of GABAA receptors at inhibitory synapses.
Proc Natl Acad Sci U S A
; 114(44): 11763-11768, 2017 10 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-29078280
8.
Deficits in the activity of presynaptic γ-aminobutyric acid type B receptors contribute to altered neuronal excitability in fragile X syndrome.
J Biol Chem
; 292(16): 6621-6632, 2017 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28213518
9.
Postsynaptic GABAB receptor activity regulates excitatory neuronal architecture and spatial memory.
J Neurosci
; 34(3): 804-16, 2014 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24431439
10.
Glutamine synthetase stability and subcellular distribution in astrocytes are regulated by γ-aminobutyric type B receptors.
J Biol Chem
; 289(42): 28808-15, 2014 Oct 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25172509
11.
Sodium channel cleavage is associated with aberrant neuronal activity and cognitive deficits in a mouse model of Alzheimer's disease.
J Neurosci
; 33(16): 7020-6, 2013 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-23595759
12.
Diversity of US participants in AstraZeneca-sponsored clinical trials.
Contemp Clin Trials
; 140: 107496, 2024 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38467274
13.
Prolonged activation of NMDA receptors promotes dephosphorylation and alters postendocytic sorting of GABAB receptors.
Proc Natl Acad Sci U S A
; 107(31): 13918-23, 2010 Aug 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-20643948
14.
Immunogenicity and safety of AZD2816, a beta (B.1.351) variant COVID-19 vaccine, and AZD1222 (ChAdOx1 nCoV-19) as third-dose boosters for previously vaccinated adults: a multicentre, randomised, partly double-blinded, phase 2/3 non-inferiority immunobridging study in the UK and Poland.
Lancet Microbe
; 4(11): e863-e874, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37783221
15.
Novel triazines as potent and selective phosphodiesterase 10A inhibitors.
Bioorg Med Chem Lett
; 22(18): 5876-84, 2012 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22902656
16.
GABA(A) receptor membrane trafficking regulates spine maturity.
Proc Natl Acad Sci U S A
; 106(30): 12500-5, 2009 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-19617557
17.
Activation of estrogen receptor-beta regulates hippocampal synaptic plasticity and improves memory.
Nat Neurosci
; 11(3): 334-43, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18297067
18.
Efficacy and safety of intramuscular administration of tixagevimab-cilgavimab for early outpatient treatment of COVID-19 (TACKLE): a phase 3, randomised, double-blind, placebo-controlled trial.
Lancet Respir Med
; 10(10): 985-996, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35688164
19.
Human genetics uncovers MAP3K15 as an obesity-independent therapeutic target for diabetes.
Sci Adv
; 8(46): eadd5430, 2022 11 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36383675
20.
The SARS-CoV-2 monoclonal antibody combination, AZD7442, is protective in nonhuman primates and has an extended half-life in humans.
Sci Transl Med
; 14(635): eabl8124, 2022 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35076282