Detalhe da pesquisa
1.
The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape.
Nature
; 573(7773): 281-286, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31485078
2.
The molecular landscape of ETMR at diagnosis and relapse.
Nature
; 576(7786): 274-280, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31802000
3.
A multi-omic single cell sequencing approach to develop a CD8 T cell specific gene signature for anti-PD1 response in solid tumors.
Int J Cancer
; 151(11): 2043-2054, 2022 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35932450
4.
Mutations in C5ORF42 cause Joubert syndrome in the French Canadian population.
Am J Hum Genet
; 90(4): 693-700, 2012 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-22425360
5.
Mutation in the nuclear-encoded mitochondrial isoleucyl-tRNA synthetase IARS2 in patients with cataracts, growth hormone deficiency with short stature, partial sensorineural deafness, and peripheral neuropathy or with Leigh syndrome.
Hum Mutat
; 35(11): 1285-9, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25130867
6.
mRMRe: an R package for parallelized mRMR ensemble feature selection.
Bioinformatics
; 29(18): 2365-8, 2013 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23825369
7.
Epigenetic dysregulation: a novel pathway of oncogenesis in pediatric brain tumors.
Acta Neuropathol
; 128(5): 615-27, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25077668
8.
Identification of FAT3 as a new candidate gene for adolescent idiopathic scoliosis.
Sci Rep
; 12(1): 12298, 2022 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35853984
9.
Biomarker analysis from CheckMate 214: nivolumab plus ipilimumab versus sunitinib in renal cell carcinoma.
J Immunother Cancer
; 10(3)2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35304405
10.
Mutations in a novel serine protease PRSS56 in families with nanophthalmos.
Mol Vis
; 17: 1850-61, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21850159
11.
Pan-cancer analysis of the effect of biopsy site on tumor mutational burden observations.
Commun Med (Lond)
; 1: 56, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-35602225
12.
Molecular correlates of response to nivolumab at baseline and on treatment in patients with RCC.
J Immunother Cancer
; 9(3)2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33658305
13.
STK11 and KEAP1 mutations as prognostic biomarkers in an observational real-world lung adenocarcinoma cohort.
ESMO Open
; 5(2)2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32312757
14.
H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis.
Nat Commun
; 10(1): 1262, 2019 03 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30890717
15.
Impaired H3K36 methylation defines a subset of head and neck squamous cell carcinomas.
Nat Genet
; 49(2): 180-185, 2017 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-28067913
16.
Spatial heterogeneity in medulloblastoma.
Nat Genet
; 49(5): 780-788, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-28394352
17.
Spatial and temporal homogeneity of driver mutations in diffuse intrinsic pontine glioma.
Nat Commun
; 7: 11185, 2016 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27048880
18.
Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape.
Science
; 352(6287): 844-9, 2016 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-27174990
19.
Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR.
Nat Genet
; 46(1): 39-44, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24316981
20.
Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma.
Nat Genet
; 46(5): 462-6, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24705250