Detalhe da pesquisa
1.
Pharmacological Activation of Nrf2 Enhances Functional Liver Regeneration.
Hepatology
; 74(2): 973-986, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33872408
2.
Characterization of Clozapine-Responsive Human T Cells.
J Immunol
; 205(9): 2375-2390, 2020 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32989092
3.
Evaluation of clinical and genetic factors in the population pharmacokinetics of carbamazepine.
Br J Clin Pharmacol
; 87(6): 2572-2588, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33217013
4.
Systems analysis of miRNA biomarkers to inform drug safety.
Arch Toxicol
; 95(11): 3475-3495, 2021 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-34510227
5.
Alternatively activated macrophages promote resolution of necrosis following acute liver injury.
J Hepatol
; 73(2): 349-360, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32169610
6.
Expression of Concern to: Diet restriction inhibits apoptosis and HMGB1 oxidation and promotes inflammatory cell recruitment during acetaminophen hepatoxicity.
Mol Med
; 26(1): 13, 2020 01 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32000658
7.
Exosomal Transport of Hepatocyte-Derived Drug-Modified Proteins to the Immune System.
Hepatology
; 70(5): 1732-1749, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31070244
8.
The utility of a differentiated preclinical liver model, HepaRG cells, in investigating delayed toxicity via inhibition of mitochondrial-replication induced by fialuridine.
Toxicol Appl Pharmacol
; 403: 115163, 2020 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32730777
9.
Definition of the Chemical and Immunological Signals Involved in Drug-Induced Liver Injury.
Chem Res Toxicol
; 33(1): 61-76, 2020 01 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31682113
10.
Cell Membrane Transporters Facilitate the Accumulation of Hepatocellular Flucloxacillin Protein Adducts: Implication in Flucloxacillin-Induced Liver Injury.
Chem Res Toxicol
; 33(12): 2939-2943, 2020 12 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33169987
11.
Stem cell models as an in vitro model for predictive toxicology.
Biochem J
; 476(7): 1149-1158, 2019 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30988136
12.
Dose-linearity of the pharmacokinetics of an intravenous [14 C]midazolam microdose in children.
Br J Clin Pharmacol
; 85(10): 2332-2340, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31269280
13.
Definition of the Nature and Hapten Threshold of the ß-Lactam Antigen Required for T Cell Activation In Vitro and in Patients.
J Immunol
; 198(11): 4217-4227, 2017 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28438900
14.
The Effect of Inhibitory Signals on the Priming of Drug Hapten-Specific T Cells That Express Distinct Vß Receptors.
J Immunol
; 199(4): 1223-1237, 2017 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28687658
15.
Characterisation of the NRF2 transcriptional network and its response to chemical insult in primary human hepatocytes: implications for prediction of drug-induced liver injury.
Arch Toxicol
; 93(2): 385-399, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30426165
16.
ß-Lactam hypersensitivity involves expansion of circulating and skin-resident TH22 cells.
J Allergy Clin Immunol
; 141(1): 235-249.e8, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28219704
17.
TEMPORARY REMOVAL: Reference intervals for putative biomarkers of drug-induced liver injury and liver regeneration in healthy human volunteers.
J Hepatol
; 2018 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29729369
18.
Stem cell-derived models to improve mechanistic understanding and prediction of human drug-induced liver injury.
Hepatology
; 65(2): 710-721, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27775817
19.
Application of in Vitro T Cell Assay Using Human Leukocyte Antigen-Typed Healthy Donors for the Assessment of Drug Immunogenicity.
Chem Res Toxicol
; 31(3): 165-167, 2018 03 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29436218
20.
HLA-A*33:03-Restricted Activation of Ticlopidine-Specific T-Cells from Human Donors.
Chem Res Toxicol
; 31(10): 1022-1024, 2018 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30179004