Detalhe da pesquisa
1.
Exploring the plasticity of the InhA substrate-binding site using new diaryl ether inhibitors.
Bioorg Chem
; 143: 107032, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38128204
2.
Mycobacterium abscessus Infections in Cystic Fibrosis Individuals: A Review on Therapeutic Options.
Int J Mol Sci
; 24(5)2023 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36902066
3.
New Drugs and Novel Cellular Targets against Tuberculosis.
Int J Mol Sci
; 23(22)2022 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36430162
4.
The Veterinary Anti-Parasitic Selamectin Is a Novel Inhibitor of the Mycobacterium tuberculosis DprE1 Enzyme.
Int J Mol Sci
; 23(2)2022 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35054958
5.
Gut Microbial Signatures in Sporadic and Hereditary Colorectal Cancer.
Int J Mol Sci
; 22(3)2021 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33525662
6.
The Antimalarial Mefloquine Shows Activity against Mycobacterium abscessus, Inhibiting Mycolic Acid Metabolism.
Int J Mol Sci
; 22(16)2021 Aug 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34445239
7.
First triclosan-based macrocyclic inhibitors of InhA enzyme.
Bioorg Chem
; 95: 103498, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31855823
8.
Mycobacterium abscessus, an Emerging and Worrisome Pathogen among Cystic Fibrosis Patients.
Int J Mol Sci
; 20(23)2019 Nov 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31766758
9.
Mechanochemical Synthesis and Biological Evaluation of Novel Isoniazid Derivatives with Potent Antitubercular Activity.
Molecules
; 22(9)2017 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28862683
10.
The Redox State Regulates the Conformation of Rv2466c to Activate the Antitubercular Prodrug TP053.
J Biol Chem
; 290(52): 31077-89, 2015 Dec 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26546681
11.
Differential roles of RND efflux pumps in antimicrobial drug resistance of sessile and planktonic Burkholderia cenocepacia cells.
Antimicrob Agents Chemother
; 58(12): 7424-9, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25267676
12.
The DprE1 enzyme, one of the most vulnerable targets of Mycobacterium tuberculosis.
Appl Microbiol Biotechnol
; 97(20): 8841-8, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24037308
13.
Expanding the knowledge around antitubercular 5-(2-aminothiazol-4-yl)isoxazole-3-carboxamides: Hit-to-lead optimization and release of a novel antitubercular chemotype via scaffold derivatization.
Eur J Med Chem
; 245(Pt 2): 114916, 2023 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36399878
14.
CanB, a Druggable Cellular Target in Mycobacterium tuberculosis.
ACS Omega
; 8(28): 25209-25220, 2023 Jul 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37483251
15.
Implementing best practices on data generation and reporting of Mycobacterium tuberculosis in vitro assays within the ERA4TB consortium.
iScience
; 26(4): 106411, 2023 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37091238
16.
MmpL3 is the cellular target of the antitubercular pyrrole derivative BM212.
Antimicrob Agents Chemother
; 56(1): 324-31, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22024828
17.
Antituberculars which target decaprenylphosphoryl-ß-D-ribofuranose 2'-oxidase DprE1: state of art.
Appl Microbiol Biotechnol
; 94(4): 907-16, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22526781
18.
A New Benzothiazolthiazolidine Derivative, 11726172, Is Active In Vitro, In Vivo, and against Nonreplicating Cells of Mycobacterium tuberculosis.
mSphere
; 7(6): e0036922, 2022 12 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36377880
19.
Biological and structural characterization of the Mycobacterium smegmatis nitroreductase NfnB, and its role in benzothiazinone resistance.
Mol Microbiol
; 77(5): 1172-85, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20624223
20.
Nitric oxide-releasing compounds for the treatment of lung infections.
Drug Discov Today
; 26(2): 542-550, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33181094