Detalhe da pesquisa
1.
Triazolopyridine ethers as potent, orally active mGlu2 positive allosteric modulators for treating schizophrenia.
Bioorg Med Chem
; 25(2): 496-513, 2017 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27914948
2.
Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers.
Proc Natl Acad Sci U S A
; 108(37): 15366-71, 2011 Sep 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-21896751
3.
Molecular characterization and identification of surrogate substrates for diacylglycerol lipase α.
Biochem Biophys Res Commun
; 411(4): 809-14, 2011 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-21787747
4.
Discovery of Orally Active Isofuranones as Potent, Selective Inhibitors of Hematopoetic Progenitor Kinase 1.
ACS Med Chem Lett
; 12(3): 443-450, 2021 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33732413
5.
Inhibitors of HIV-1 attachment. Part 3: A preliminary survey of the effect of structural variation of the benzamide moiety on antiviral activity.
Bioorg Med Chem Lett
; 19(17): 5136-9, 2009 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19632112
6.
Inhibitors of HIV-1 attachment. Part 2: An initial survey of indole substitution patterns.
Bioorg Med Chem Lett
; 19(7): 1977-81, 2009 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19251416
7.
Discovery of the Human Immunodeficiency Virus Type 1 (HIV-1) Attachment Inhibitor Temsavir and Its Phosphonooxymethyl Prodrug Fostemsavir.
J Med Chem
; 61(14): 6308-6327, 2018 07 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29920093
8.
BMS-986163, a Negative Allosteric Modulator of GluN2B with Potential Utility in Major Depressive Disorder.
ACS Med Chem Lett
; 9(5): 472-477, 2018 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29795762
9.
Structure Determination of the Products from the Acid-Catalyzed Condensation of Indole with Acetone.
J Org Chem
; 61(2): 451-454, 1996 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-11666959
10.
Identification of small molecules that selectively inhibit diacylglycerol lipase-α activity.
J Biomol Screen
; 19(4): 595-605, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24241710
11.
HCV NS5A replication complex inhibitors. Part 4. Optimization for genotype 1a replicon inhibitory activity.
J Med Chem
; 57(5): 1976-94, 2014 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-23573957
12.
E-novo: an automated workflow for efficient structure-based lead optimization.
J Chem Inf Model
; 49(7): 1797-809, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19552372
13.
Respiratory syncytial virus fusion inhibitors. Part 6: an examination of the effect of structural variation of the benzimidazol-2-one heterocycle moiety.
Bioorg Med Chem Lett
; 17(17): 4784-90, 2007 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17616396
14.
An empirical process for the design of high-throughput screening deck filters.
J Chem Inf Model
; 46(3): 1060-8, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-16711725
15.
Respiratory syncytial virus fusion inhibitors. Part 3: Water-soluble benzimidazol-2-one derivatives with antiviral activity in vivo.
Bioorg Med Chem Lett
; 16(5): 1115-22, 2006 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16368233
16.
Respiratory syncytial virus inhibitors. Part 2: Benzimidazol-2-one derivatives.
Bioorg Med Chem Lett
; 14(5): 1133-7, 2004 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-14980651