Detalhe da pesquisa
1.
Functional and structural asymmetry suggest a unifying principle for catalysis in membrane-bound pyrophosphatases.
EMBO Rep
; 25(2): 853-875, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38182815
2.
Liquid application method for time-resolved analyses by serial synchrotron crystallography.
Nat Methods
; 16(10): 979-982, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31527838
3.
Structure and diffusive dynamics of aspartate α-decarboxylase (ADC) liganded with D-serine in aqueous solution.
Phys Chem Chem Phys
; 24(34): 20336-20347, 2022 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-35980136
4.
The HARE chip for efficient time-resolved serial synchrotron crystallography.
J Synchrotron Radiat
; 27(Pt 2): 360-370, 2020 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32153274
5.
Extending enzyme molecular recognition with an expanded amino acid alphabet.
Proc Natl Acad Sci U S A
; 114(10): 2610-2615, 2017 03 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28196894
6.
Directed Assembly of Homopentameric Cholera Toxin B-Subunit Proteins into Higher-Order Structures Using Coiled-Coil Appendages.
J Am Chem Soc
; 141(13): 5211-5219, 2019 04 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30856321
7.
Oxygen Activation Switch in the Copper Amine Oxidase of Escherichia coli.
Biochemistry
; 57(36): 5301-5314, 2018 09 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30110143
8.
The Mechanism of Regulation of Pantothenate Biosynthesis by the PanD-PanZ·AcCoA Complex Reveals an Additional Mode of Action for the Antimetabolite N-Pentyl Pantothenamide (N5-Pan).
Biochemistry
; 56(37): 4931-4939, 2017 09 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28832133
9.
Topological Dissection of the Membrane Transport Protein Mhp1 Derived from Cysteine Accessibility and Mass Spectrometry.
Anal Chem
; 89(17): 8844-8852, 2017 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28726379
10.
Time-resolved crystallography using the Hadamard transform.
Nat Methods
; 11(11): 1131-4, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25282611
11.
Evaluation of fluoropyruvate as nucleophile in reactions catalysed by N-acetyl neuraminic acid lyase variants: scope, limitations and stereoselectivity.
Org Biomol Chem
; 14(1): 105-12, 2016 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26537532
12.
In pursuit of an accurate spatial and temporal model of biomolecules at the atomistic level: a perspective on computer simulation.
Acta Crystallogr D Biol Crystallogr
; 71(Pt 1): 162-72, 2015 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25615870
13.
Probing the molecular mechanisms in copper amine oxidases by generating heterodimers.
Chembiochem
; 16(4): 559-64, 2015 Mar 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-25607656
14.
Limits of structural plasticity in a picornavirus capsid revealed by a massively expanded equine rhinitis A virus particle.
J Virol
; 88(11): 6093-9, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24648455
15.
Structure-guided design affirms inhibitors of hepatitis C virus p7 as a viable class of antivirals targeting virion release.
Hepatology
; 59(2): 408-22, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24022996
16.
Threonine 57 is required for the post-translational activation of Escherichia coli aspartate α-decarboxylase.
Acta Crystallogr D Biol Crystallogr
; 70(Pt 4): 1166-72, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24699660
17.
Human cellular retinaldehyde-binding protein has secondary thermal 9-cis-retinal isomerase activity.
J Am Chem Soc
; 136(1): 137-46, 2014 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-24328211
18.
Investigation of how gate residues in the main channel affect the catalytic activity of Scytalidium thermophilum catalase.
Acta Crystallogr D Struct Biol
; 80(Pt 2): 101-112, 2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38265876
19.
An ultraviolet-driven rescue pathway for oxidative stress to eye lens protein human gamma-D crystallin.
Commun Chem
; 7(1): 81, 2024 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38600176
20.
Multiple redox switches of the SARS-CoV-2 main protease in vitro provide opportunities for drug design.
Nat Commun
; 15(1): 411, 2024 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38195625