Detalhe da pesquisa
1.
HBO1 is required for the maintenance of leukaemia stem cells.
Nature
; 577(7789): 266-270, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31827282
2.
Enhancing PET Degrading Enzymes: A Combinatory Approach.
Chembiochem
; 25(10): e202400084, 2024 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38584134
3.
Cryo-EM structure of the active, Gs-protein complexed, human CGRP receptor.
Nature
; 561(7724): 492-497, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30209400
4.
Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth.
Nature
; 560(7717): 253-257, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30069049
5.
Privileged scaffolds in medicinal chemistry: Studies on pyrazolo[1,5-a]pyrimidines on sulfonamide containing Carbonic Anhydrase inhibitors.
Bioorg Med Chem Lett
; 49: 128309, 2021 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34371130
6.
The Glitazone Class of Drugs as Carbonic Anhydrase Inhibitors-A Spin-Off Discovery from Fragment Screening.
Molecules
; 26(10)2021 May 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34070212
7.
X-ray crystallography of Epacadostat in adduct with Carbonic Anhydrase IX.
Bioorg Chem
; 97: 103669, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32088421
8.
Structural Basis for the Allosteric Regulation of the SbtA Bicarbonate Transporter by the PII-like Protein, SbtB, from Cyanobium sp. PCC7001.
Biochemistry
; 58(50): 5030-5039, 2019 12 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31746199
9.
An unexpected vestigial protein complex reveals the evolutionary origins of an s-triazine catabolic enzyme.
J Biol Chem
; 293(20): 7880-7891, 2018 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-29523689
10.
T-dependent B cell responses to Plasmodium induce antibodies that form a high-avidity multivalent complex with the circumsporozoite protein.
PLoS Pathog
; 13(7): e1006469, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28759640
11.
8-Mercaptoguanine Derivatives as Inhibitors of Dihydropteroate Synthase.
Chemistry
; 24(8): 1922-1930, 2018 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29171692
12.
Synthesis, structure and bioactivity of primary sulfamate-containing natural products.
Bioorg Med Chem Lett
; 28(17): 3009-3013, 2018 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29685656
13.
High-Resolution X-Ray Structures of Two Functionally Distinct Members of the Cyclic Amide Hydrolase Family of Toblerone Fold Enzymes.
Appl Environ Microbiol
; 83(9)2017 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28235873
14.
Some of the most interesting CASP11 targets through the eyes of their authors.
Proteins
; 84 Suppl 1: 34-50, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26473983
15.
A ß-Alanine Catabolism Pathway Containing a Highly Promiscuous ω-Transaminase in the 12-Aminododecanate-Degrading Pseudomonas sp. Strain AAC.
Appl Environ Microbiol
; 82(13): 3846-3856, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27107110
16.
Structural and biochemical analyses of a Clostridium perfringens sortase D transpeptidase.
Acta Crystallogr D Biol Crystallogr
; 71(Pt 7): 1505-13, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26143922
17.
X-ray structure of the amidase domain of AtzF, the allophanate hydrolase from the cyanuric acid-mineralizing multienzyme complex.
Appl Environ Microbiol
; 81(2): 470-80, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25362066
18.
Crystal structure of an indole-3-acetic acid amido synthetase from grapevine involved in auxin homeostasis.
Plant Cell
; 24(11): 4525-38, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23136372
19.
Nitrate in the active site of protein tyrosine phosphatase 1B is a putative mimetic of the transition state.
Acta Crystallogr D Biol Crystallogr
; 70(Pt 2): 565-71, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24531490
20.
The structure of vanin 1: a key enzyme linking metabolic disease and inflammation.
Acta Crystallogr D Biol Crystallogr
; 70(Pt 12): 3320-9, 2014 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25478849