Detalhe da pesquisa
1.
A glycyl radical enzyme enables hydrogen sulfide production by the human intestinal bacterium Bilophila wadsworthia.
Proc Natl Acad Sci U S A
; 116(8): 3171-3176, 2019 02 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30718429
2.
Use of the dehydrophos biosynthetic enzymes to prepare antimicrobial analogs of alaphosphin.
Org Biomol Chem
; 17(4): 822-829, 2019 01 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-30608108
3.
O-H Activation by an Unexpected Ferryl Intermediate during Catalysis by 2-Hydroxyethylphosphonate Dioxygenase.
J Am Chem Soc
; 139(5): 2045-2052, 2017 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28092705
4.
Go it alone: four-electron oxidations by mononuclear non-heme iron enzymes.
J Biol Inorg Chem
; 22(2-3): 381-394, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27783267
5.
Oxygen-18 Kinetic Isotope Effects of Nonheme Iron Enzymes HEPD and MPnS Support Iron(III) Superoxide as the Hydrogen Abstraction Species.
J Am Chem Soc
; 137(33): 10448-51, 2015 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26267117
6.
A common late-stage intermediate in catalysis by 2-hydroxyethyl-phosphonate dioxygenase and methylphosphonate synthase.
J Am Chem Soc
; 137(9): 3217-20, 2015 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-25699631
7.
Biochemistry: Positive and radical.
Nature
; 496(7443): 34-5, 2013 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-23552937
8.
Mechanistic investigation of methylphosphonate synthase, a non-heme iron-dependent oxygenase.
J Am Chem Soc
; 134(38): 15660-3, 2012 Sep 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-22957470
9.
Mechanism and substrate recognition of 2-hydroxyethylphosphonate dioxygenase.
Biochemistry
; 50(30): 6598-605, 2011 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-21711001
10.
On the stereochemistry of 2-hydroxyethylphosphonate dioxygenase.
J Am Chem Soc
; 133(12): 4236-9, 2011 Mar 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-21381767
11.
Structural basis for methylphosphonate biosynthesis.
Science
; 358(6368): 1336-1339, 2017 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29217579
12.
Structure and function of phosphonoacetaldehyde dehydrogenase: the missing link in phosphonoacetate formation.
Chem Biol
; 21(1): 125-35, 2014 Jan 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-24361046
13.
Phosphonate biosynthesis and catabolism: a treasure trove of unusual enzymology.
Curr Opin Chem Biol
; 17(4): 580-8, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23870698
14.
Evidence that the fosfomycin-producing epoxidase, HppE, is a non-heme-iron peroxidase.
Science
; 342(6161): 991-5, 2013 Nov 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-24114783
15.
Discovery and biosynthesis of phosphonate and phosphinate natural products.
Methods Enzymol
; 516: 101-23, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23034226
16.
Stereochemistry of Hydride Transfer by Group III Alcohol Dehydrogenases Involved in Phosphonate Biosynthesis.
Medchemcomm
; 3(8): 967-970, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25400901