Detalhe da pesquisa
1.
Discovery of (E)-3-(4-chlorophenyl)-N-(5-hydroxypentyl)acrylamide among N-substituted cinnamamide derivatives as a novel cosmetic ingredient for hyperpigmentation.
Bioorg Chem
; 150: 107533, 2024 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38878750
2.
lIn vitro safety evaluation of (6-methoxy-9-oxo-9H-xanthen-2-yl)methyl (E)-3-(2,4-dimethoxyphenyl)acrylate (K-116) - the novel potential UV filter designed by means of a double chromophore strategy.
Xenobiotica
; : 1-20, 2024 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-38819995
3.
Comparative study on ABCB1-dependent efflux of anthracyclines and their metabolites: consequences for cancer resistance.
Xenobiotica
; 53(6-7): 507-514, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37753851
4.
In Silico and In Vitro Assessment of Carbonyl Reductase 1 Inhibition Using ASP9521-A Potent Aldo-Keto Reductase 1C3 Inhibitor with the Potential to Support Anticancer Therapy Using Anthracycline Antibiotics.
Molecules
; 28(9)2023 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37175180
5.
In silico and in vitro ADME-Tox analysis and in vivo pharmacokinetic study of representative pan-PDE inhibitors from the group of 7,8-disubstituted derivatives of 1,3-dimethyl-7H-purine-2,6-dione.
Toxicol Appl Pharmacol
; 457: 116318, 2022 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36414119
6.
Evaluation of Two Novel Hydantoin Derivatives Using Reconstructed Human Skin Model EpiskinTM: Perspectives for Application as Potential Sunscreen Agents.
Molecules
; 27(6)2022 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35335215
7.
Autophagy modulating agents as chemosensitizers for cisplatin therapy in cancer.
Invest New Drugs
; 39(2): 538-563, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33159673
8.
Synthesis and in vitro evaluation of anti-inflammatory, antioxidant, and anti-fibrotic effects of new 8-aminopurine-2,6-dione-based phosphodiesterase inhibitors as promising anti-asthmatic agents.
Bioorg Chem
; 117: 105409, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34749117
9.
Neuropathic pain-alleviating activity of novel 5-HT6 receptor inverse agonists derived from 2-aryl-1H-pyrrole-3-carboxamide.
Bioorg Chem
; 115: 105218, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34365058
10.
Cinnamic Acid Derivatives as Cardioprotective Agents against Oxidative and Structural Damage Induced by Doxorubicin.
Int J Mol Sci
; 22(12)2021 Jun 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34207549
11.
Synthesis, Anticonvulsant, and Antinociceptive Activity of New 3-(2-Chlorophenyl)- and 3-(3-Chlorophenyl)-2,5-dioxo-pyrrolidin-1-yl-acetamides.
Molecules
; 26(6)2021 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33809109
12.
(+)-Usnic Acid as a Promising Candidate for a Safe and Stable Topical Photoprotective Agent.
Molecules
; 26(17)2021 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34500657
13.
Anticonvulsant and analgesic in neuropathic pain activity in a group of new aminoalkanol derivatives.
Bioorg Med Chem Lett
; 30(16): 127325, 2020 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32631530
14.
Correction to: Fibroblast-to-myofibroblast transition in bronchial asthma.
Cell Mol Life Sci
; 76(1): 209, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30155648
15.
The Involvement of Xanthone and (E)-Cinnamoyl Chromophores for the Design and Synthesis of Novel Sunscreening Agents.
Int J Mol Sci
; 22(1)2020 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33375127
16.
A Novel, Pan-PDE Inhibitor Exerts Anti-Fibrotic Effects in Human Lung Fibroblasts via Inhibition of TGF-ß Signaling and Activation of cAMP/PKA Signaling.
Int J Mol Sci
; 21(11)2020 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32503342
17.
S(+)-(2E)-N-(2-Hydroxypropyl)-3-Phenylprop-2-Enamide (KM-568): A Novel Cinnamamide Derivative with Anticonvulsant Activity in Animal Models of Seizures and Epilepsy.
Int J Mol Sci
; 21(12)2020 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32575479
18.
Impact of N-Alkylamino Substituents on Serotonin Receptor (5-HTR) Affinity and Phosphodiesterase 10A (PDE10A) Inhibition of Isoindole-1,3-dione Derivatives.
Molecules
; 25(17)2020 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32854402
19.
Novel multitarget 5-arylidenehydantoins with arylpiperazinealkyl fragment: Pharmacological evaluation and investigation of cytotoxicity and metabolic stability.
Bioorg Med Chem
; 27(18): 4163-4173, 2019 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31383628
20.
Fibroblast-to-myofibroblast transition in bronchial asthma.
Cell Mol Life Sci
; 75(21): 3943-3961, 2018 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-30101406