Detalhe da pesquisa
1.
First-in-human phase 1 study of budigalimab, an anti-PD-1 inhibitor, in patients with non-small cell lung cancer and head and neck squamous cell carcinoma.
Cancer Immunol Immunother
; 71(2): 417-431, 2022 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-34216247
2.
Nivolumab monotherapy or combination with ipilimumab with or without cobimetinib in previously treated patients with pancreatic adenocarcinoma (CheckMate 032).
J Immunother Cancer
; 12(2)2024 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38316517
3.
Safety, efficacy, and biological data of T cell-enabling oncolytic adenovirus TILT-123 in advanced solid cancers from the TUNIMO monotherapy phase I trial.
Clin Cancer Res
; 2024 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38546220
4.
ODM-204, a Novel Dual Inhibitor of CYP17A1 and Androgen Receptor: Early Results from Phase I Dose Escalation in Men with Castration-resistant Prostate Cancer.
Eur Urol Focus
; 6(1): 63-70, 2020 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30194031
5.
Phase I/IIa, open-label, multicentre study to evaluate the optimal dosing and safety of ODM-203 in patients with advanced or metastatic solid tumours.
ESMO Open
; 5(6): e001081, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33262202
6.
Pim-1 kinase phosphorylates RUNX family transcription factors and enhances their activity.
BMC Cell Biol
; 7: 21, 2006 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-16684349
7.
Pim-1 kinase promotes inactivation of the pro-apoptotic Bad protein by phosphorylating it on the Ser112 gatekeeper site.
FEBS Lett
; 571(1-3): 43-9, 2004 Jul 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-15280015
8.
Attenuation of androgen receptor-dependent transcription by the serine/threonine kinase Pim-1.
Lab Invest
; 83(9): 1301-9, 2003 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-13679438
9.
Pim-1 kinase inhibits STAT5-dependent transcription via its interactions with SOCS1 and SOCS3.
Blood
; 103(10): 3744-50, 2004 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-14764533