Detalhe da pesquisa
1.
Elevated APOBEC3B expression drives a kataegic-like mutation signature and replication stress-related therapeutic vulnerabilities in p53-defective cells.
Br J Cancer
; 117(1): 113-123, 2017 Jun 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28535155
2.
SF3B1 hotspot mutations confer sensitivity to PARP inhibition by eliciting a defective replication stress response.
Nat Genet
; 55(8): 1311-1323, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37524790
3.
A Flexible, Pooled CRISPR Library for Drug Development Screens.
CRISPR J
; 3(3): 211-222, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33054419
4.
Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance.
Nat Commun
; 9(1): 1849, 2018 05 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29748565
5.
Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAness.
Sci Rep
; 8(1): 10614, 2018 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30006631
6.
Author Correction: Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAness.
Sci Rep
; 8(1): 12771, 2018 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30131505
7.
E-Cadherin/ROS1 Inhibitor Synthetic Lethality in Breast Cancer.
Cancer Discov
; 8(4): 498-515, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29610289
8.
Functional diversity and cooperativity between subclonal populations of pediatric glioblastoma and diffuse intrinsic pontine glioma cells.
Nat Med
; 24(8): 1204-1215, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29967352
9.
Genome-wide barcoded transposon screen for cancer drug sensitivity in haploid mouse embryonic stem cells.
Sci Data
; 4: 170020, 2017 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28248920
10.
ATR Is a Therapeutic Target in Synovial Sarcoma.
Cancer Res
; 77(24): 7014-7026, 2017 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29038346
11.
Modeling Therapy Resistance in BRCA1/2-Mutant Cancers.
Mol Cancer Ther
; 16(9): 2022-2034, 2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28619759
12.
ATR inhibitors as a synthetic lethal therapy for tumours deficient in ARID1A.
Nat Commun
; 7: 13837, 2016 12 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-27958275
13.
Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines.
Cell Rep
; 14(10): 2490-501, 2016 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26947069
14.
Breast cancer intratumor genetic heterogeneity: causes and implications.
Expert Rev Anticancer Ther
; 12(8): 1021-32, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23030222
15.
MicroRNA regulation of Cbx7 mediates a switch of Polycomb orthologs during ESC differentiation.
Cell Stem Cell
; 10(1): 33-46, 2012 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-22226354
16.
Modified cell cycle status in a mouse model of altered neuronal vulnerability (slow Wallerian degeneration; Wlds).
Genome Biol
; 9(6): R101, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18570652