Detalhe da pesquisa
1.
Viral-based animal models in polyglutamine disorders.
Brain
; 147(4): 1166-1189, 2024 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38284949
2.
Blood and cerebellar abundance of ATXN3 splice variants in spinocerebellar ataxia type 3/Machado-Joseph disease.
Neurobiol Dis
; 193: 106456, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38423193
3.
The stress granule protein G3BP1 alleviates spinocerebellar ataxia-associated deficits.
Brain
; 146(6): 2346-2363, 2023 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36511898
4.
Blood transcriptome sequencing identifies biomarkers able to track disease stages in spinocerebellar ataxia type 3.
Brain
; 146(10): 4132-4143, 2023 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37071051
5.
Extracellular communication between brain cells through functional transfer of Cre mRNA mediated by extracellular vesicles.
Mol Ther
; 31(7): 2220-2239, 2023 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37194237
6.
Extracellular vesicle-based delivery of silencing sequences for the treatment of Machado-Joseph disease/spinocerebellar ataxia type 3.
Mol Ther
; 31(5): 1275-1292, 2023 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37025062
7.
Modeling Lysosomal Storage Disorders in an Innovative Way: Establishment and Characterization of Stem Cell Lines from Human Exfoliated Deciduous Teeth of Mucopolysaccharidosis Type II Patients.
Int J Mol Sci
; 25(6)2024 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38542525
8.
ULK overexpression mitigates motor deficits and neuropathology in mouse models of Machado-Joseph disease.
Mol Ther
; 30(1): 370-387, 2022 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34298131
9.
A new protocol for whole-brain biodistribution analysis of AAVs by tissue clearing, light-sheet microscopy and semi-automated spatial quantification.
Gene Ther
; 29(12): 665-679, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36316447
10.
Identification of the calpain-generated toxic fragment of ataxin-3 protein provides new avenues for therapy of Machado-Joseph disease| Spinocerebellar ataxia type 3.
Neuropathol Appl Neurobiol
; 48(1): e12748, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34273111
11.
The autophagy-enhancing drug carbamazepine improves neuropathology and motor impairment in mouse models of Machado-Joseph disease.
Neuropathol Appl Neurobiol
; 48(1): e12763, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34432315
12.
Characterization of Lifestyle in Spinocerebellar Ataxia Type 3 and Association with Disease Severity.
Mov Disord
; 37(2): 405-410, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34713931
13.
Differential Temporal Dynamics of Axial and Appendicular Ataxia in SCA3.
Mov Disord
; 37(9): 1850-1860, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35808813
14.
Tau and neurofilament light-chain as fluid biomarkers in spinocerebellar ataxia type 3.
Eur J Neurol
; 29(8): 2439-2452, 2022 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-35478426
15.
SIRT2 Deficiency Exacerbates Hepatic Steatosis via a Putative Role of the ER Stress Pathway.
Int J Mol Sci
; 23(12)2022 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35743232
16.
Ibuprofen enhances synaptic function and neural progenitors proliferation markers and improves neuropathology and motor coordination in Machado-Joseph disease models.
Hum Mol Genet
; 28(22): 3691-3703, 2019 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31127937
17.
Polyglutamine-Expanded Ataxin-3: A Target Engagement Marker for Spinocerebellar Ataxia Type 3 in Peripheral Blood.
Mov Disord
; 36(11): 2675-2681, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34397117
18.
Antisense oligonucleotide therapeutics in neurodegenerative diseases: the case of polyglutamine disorders.
Brain
; 143(2): 407-429, 2020 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31738395
19.
Extracellular Vesicles Physiological Role and the Particular Case of Disease-Spreading Mechanisms in Polyglutamine Diseases.
Int J Mol Sci
; 22(22)2021 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34830171
20.
Living Proof of Activity of Extracellular Vesicles in the Central Nervous System.
Int J Mol Sci
; 22(14)2021 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34298912