In vivo kinetic evaluation of an adhesive capsulitis model in rats.

BACKGROUND AND HYPOTHESIS: We hypothesized that extra-articular, internal fixation of the shoulder in rats would result in a subsequent decrease in rotational range of motion (ROM) and an increase in joint stiffness. We further hypothesized that residual kinematic changes would still be present at 8 weeks after immobilization. Extra-articular, internal fixation of the shoulder has been used to induce adhesive capsulitis in rats; however, the effects on in vivo kinematics have not been assessed. METHODS: Baseline measurements of rotational torque and ROM were acquired (n = 10 rats), and the left forelimb of each animal was immobilized with sutures passed between the scapula and the humeral shaft. After 8 weeks, the sutures were removed, and changes in kinematics and kinetics were longitudinally quantified in the follow-up period. Changes in stiffness, defined as the area under the angle-torque curve, were also quantified. RESULTS: Immediately after suture removal, there was a 63% decrease in total ROM compared with baseline (51° ± 10° vs. 136° ± 0°; P < .001). Similarly, total torque was found to increase 13.4 N.mm compared with baseline (22.6 ± 5.9 N.mm vs. 9.2 ± 2.6 N.mm; P = .002). Residual total ROM restrictions and an increased torque in internal rotation were still evident at 8 weeks of follow-up (113° ± 8° vs. 137° ± 0°, P < .001 and 3.5 ± 0.4 N.mm vs. 2.7 ± 0.7 N.mm, P = .036). Stiffness also increased after suture removal and at 8 weeks of follow-up compared with baseline. CONCLUSION: This animal model of adhesive capsulitis rendered lasting effects on in vivo kinematics of the shoulder.

The Conservative Management of an Uncommon Case of Postpartum HELLP (Hemolysis, Elevated Liver Enzymes, and Low Platelet Count) Syndrome Complicated by Liver Hematoma Causing Gastric Outlet Obstruction: A Case Report.

Hypertensive disorders of pregnancy, particularly preeclampsia, are significant contributors to maternal and fetal mortality worldwide. HELLP (hemolysis, elevated liver enzymes, and low platelet count) syndrome constitutes a severe manifestation of preeclampsia. Subcapsular liver hematoma (SLH) is a rare complication of HELLP syndrome, resulting from blood accumulation between the liver parenchyma and the Glisson's capsule. We present a unique case of a pregnant patient with HELLP syndrome complicated by SLH, leading to gastric outlet obstruction (GOO). The patient's medical history, clinical presentation, diagnostic evaluation, and management are discussed. The patient, with a history of pregnancy-induced hypertension, presented with HELLP syndrome at 34 weeks of gestation. Elevated blood pressure, liver enzymes, and low platelet count were observed. Postpartum, the patient developed SLH causing GOO. Conservative management, including intravenous fluids, pain control, and a nasogastric tube, was employed. Imaging confirmed SLH and GOO. Multidisciplinary collaboration guided the treatment approach, emphasizing close monitoring, nonoperative strategies, and dietary adjustments. The patient's condition improved, and she was discharged on postpartum day 20. This case report underscores the challenges of managing HELLP syndrome complications, especially SLH-induced GOO. Early diagnosis, appropriate medical interventions, and interdisciplinary coordination are pivotal in ensuring positive outcomes. Conservative management can be effective in stable patients, but timely recognition and monitoring remain crucial for averting potential complications. This case contributes to the limited literature on managing such complex scenarios and highlights the importance of tailored strategies in multifaceted medical conditions.

A Rare Case of Pulmonic and Aortic Valve Infective Endocarditis: A Case Report.

Infective endocarditis (IE) is a microbial infection affecting cardiac valves. IE most often affects the aortic valve and is commonly caused by community-acquired, penicillin-sensitive streptococcus that enters through the oral cavity. In this report, we present a case of a 66-year-old man with a medical history of congenital pulmonic stenosis status after pulmonic valve (PV) repair. The patient underwent a transesophageal echocardiogram showing a 1 cm × 0.7 cm mobile vegetation attached to the ventricular aspect of the right coronary aortic cusp and a 1.1 cm × 0.5 cm mobile vegetation attached to the arterial aspect of the PV cusp. In conclusion, concomitant right- and left-sided IE is an exceedingly rare condition. Due to its rarity and complexity of presentation, pulmonic valve endocarditis (PVE) requires a multidisciplinary approach to its perioperative management to prevent systemic complications.

Transfusion-Related Acute Lung Injury (TRALI) in Postoperative Anesthesia Care Unit (PACU) After One Unit of Platelets: A Case Report.

Transfusion-related acute lung injury (TRALI) following transfusion of all plasma-containing blood products is a rare but serious syndrome characterized by the acute onset of non-cardiogenic pulmonary edema with severe hypoxemia with or without symptoms of hypotension, pinkish frothy secretions, fever, and cyanosis. In this report, we present a case of a 66-year-old female with a medical history significant for hypertension, hyperlipidemia, hepatitis C, liver cirrhosis, tobacco use disorder, metastatic spindle cell carcinoma of the lung status post chemotherapy who developed TRALI after administration of one unit of platelets. Although a rare occurrence, there can be a considerable risk of TRALI following transfusion of all plasma-containing blood products and there is great importance in considering each patient's risk factors for TRALI development prior to blood product administration.