Detalhe da pesquisa
1.
A variant in myeloperoxidase promoter hastens the emergence of hepatocellular carcinoma in patients with HCV-related cirrhosis.
J Hepatol
; 56(2): 426-32, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21907168
2.
Central role of mitochondria in drug-induced liver injury.
Drug Metab Rev
; 44(1): 34-87, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21892896
3.
Hepatic mitochondrial DNA depletion after an alcohol binge in mice: probable role of peroxynitrite and modulation by manganese superoxide dismutase.
J Pharmacol Exp Ther
; 332(3): 886-97, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-20016022
4.
Myeloperoxidase and superoxide dismutase 2 polymorphisms comodulate the risk of hepatocellular carcinoma and death in alcoholic cirrhosis.
Hepatology
; 50(5): 1484-93, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19731237
5.
MnSOD overexpression prevents liver mitochondrial DNA depletion after an alcohol binge but worsens this effect after prolonged alcohol consumption in mice.
Dig Dis
; 28(6): 756-75, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-21525761
6.
Mitochondrial involvement in drug-induced liver injury.
Handb Exp Pharmacol
; (196): 311-65, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20020267
7.
Prolonged ethanol administration depletes mitochondrial DNA in MnSOD-overexpressing transgenic mice, but not in their wild type littermates.
Toxicol Appl Pharmacol
; 234(3): 326-38, 2009 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19063909
8.
The manganese superoxide dismutase Ala16Val dimorphism modulates iron accumulation in human hepatoma cells.
Free Radic Biol Med
; 45(9): 1308-17, 2008 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18760346
9.
Ibuprofen administration attenuates serum TNF-alpha levels, hepatic glutathione depletion, hepatic apoptosis and mouse mortality after Fas stimulation.
Toxicol Appl Pharmacol
; 231(3): 336-43, 2008 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18572215
10.
Steatohepatitis-inducing drugs trigger cytokeratin cross-links in hepatocytes. Possible contribution to Mallory-Denk body formation.
Toxicol In Vitro
; 22(6): 1511-9, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18603402
11.
Prediction of drug-induced liver injury in humans by using in vitro methods: the case of ximelagatran.
Toxicol In Vitro
; 22(3): 730-46, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18191936
12.
Genetic polymorphisms in antioxidant enzymes modulate hepatic iron accumulation and hepatocellular carcinoma development in patients with alcohol-induced cirrhosis.
Cancer Res
; 66(5): 2844-52, 2006 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16510607
13.
High doses of stavudine induce fat wasting and mild liver damage without impairing mitochondrial respiration in mice.
Antivir Ther
; 12(3): 389-400, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17591029
14.
Manganese superoxide dismutase dimorphism and iron overload, hepatocellular carcinoma, and death in hepatitis C virus-infected patients.
Clin Gastroenterol Hepatol
; 5(5): 630-5, 2007 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17336594
15.
Protein kinase PKC delta and c-Abl are required for mitochondrial apoptosis induction by genotoxic stress in the absence of p53, p73 and Fas receptor.
FEBS Lett
; 580(11): 2547-52, 2006 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16631755
16.
Mitochondrial dysfunction in NASH: causes, consequences and possible means to prevent it.
Mitochondrion
; 6(1): 1-28, 2006 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-16406828
17.
Partial Beclin 1 silencing aggravates doxorubicin- and Fas-induced apoptosis in HepG2 cells.
World J Gastroenterol
; 12(18): 2895-900, 2006 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-16718815
18.
Ethanol increases mitochondrial cytochrome P450 2E1 in mouse liver and rat hepatocytes.
FEBS Lett
; 579(30): 6895-902, 2005 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-16337197
19.
Hepatitis C virus core protein inhibits microsomal triglyceride transfer protein activity and very low density lipoprotein secretion: a model of viral-related steatosis.
FASEB J
; 16(2): 185-94, 2002 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-11818366
20.
The Ala16Val genetic dimorphism modulates the import of human manganese superoxide dismutase into rat liver mitochondria.
Pharmacogenetics
; 13(3): 145-57, 2003 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-12618592