Detalhe da pesquisa
1.
Engineering PD-1-targeted small protein variants for in vitro diagnostics and in vivo PET imaging.
J Transl Med
; 22(1): 426, 2024 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38711085
2.
Small protein blockers of human IL-6 receptor alpha inhibit proliferation and migration of cancer cells.
Cell Commun Signal
; 22(1): 261, 2024 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38715108
3.
ABD-Derived Protein Blockers of Human IL-17 Receptor A as Non-IgG Alternatives for Modulation of IL-17-Dependent Pro-Inflammatory Axis.
Int J Mol Sci
; 19(10)2018 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30304852
4.
p19-Targeting ILP Protein Blockers of IL-23/Th-17 Pro-Inflammatory Axis Displayed on Engineered Bacteria of Food Origin.
Int J Mol Sci
; 19(7)2018 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29966384
5.
Human interleukin-23 receptor antagonists derived from an albumin-binding domain scaffold inhibit IL-23-dependent ex vivo expansion of IL-17-producing T-cells.
Proteins
; 82(6): 975-89, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24549990
6.
Novel high-affinity binders of human interferon gamma derived from albumin-binding domain of protein G.
Proteins
; 80(3): 774-89, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22113774
7.
Myomedin replicas of gp120 V3 loop glycan epitopes recognized by PGT121 and PGT126 antibodies as non-cognate antigens for stimulation of HIV-1 broadly neutralizing antibodies.
Front Immunol
; 13: 1066361, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36569830
8.
Myomedin scaffold variants targeted to 10E8 HIV-1 broadly neutralizing antibody mimic gp41 epitope and elicit HIV-1 virus-neutralizing sera in mice.
Virulence
; 12(1): 1271-1287, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33993840
9.
Thrombus Imaging Using 3D Printed Middle Cerebral Artery Model and Preclinical Imaging Techniques: Application to Thrombus Targeting and Thrombolytic Studies.
Pharmaceutics
; 12(12)2020 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33322710
10.
Proteins mimicking epitope of HIV-1 virus neutralizing antibody induce virus-neutralizing sera in mice.
EBioMedicine
; 47: 247-256, 2019 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-31544770
11.
Targeting Human Thrombus by Liposomes Modified with Anti-Fibrin Protein Binders.
Pharmaceutics
; 11(12)2019 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31810280
12.
p19-targeted ABD-derived protein variants inhibit IL-23 binding and exert suppressive control over IL-23-stimulated expansion of primary human IL-17+ T-cells.
Autoimmunity
; 50(2): 102-113, 2017 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-28100093
13.
Cold-active beta-galactosidase from Arthrobacter sp. C2-2 forms compact 660 kDa hexamers: crystal structure at 1.9A resolution.
J Mol Biol
; 353(2): 282-94, 2005 Oct 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-16171818
14.
HIV-1 protease mutations and inhibitor modifications monitored on a series of complexes. Structural basis for the effect of the A71V mutation on the active site.
J Med Chem
; 49(19): 5777-84, 2006 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-16970402
15.
Development of Recombinant Lactococcus lactis Displaying Albumin-Binding Domain Variants against Shiga Toxin 1 B Subunit.
PLoS One
; 11(9): e0162625, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27606705
16.
Hydroxyethylamine isostere of an HIV-1 protease inhibitor prefers its amine to the hydroxy group in binding to catalytic aspartates. A synchrotron study of HIV-1 protease in complex with a peptidomimetic inhibitor.
J Med Chem
; 45(7): 1432-8, 2002 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-11906284
17.
An ethylenamine inhibitor binds tightly to both wild type and mutant HIV-1 proteases. Structure and energy study.
J Med Chem
; 46(9): 1636-44, 2003 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-12699382
18.
Increasing affinity of interferon-γ receptor 1 to interferon-γ by computer-aided design.
Biomed Res Int
; 2013: 752514, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24199198
19.
Novel binders derived from an albumin-binding domain scaffold targeting human prostate secretory protein 94 (PSP94).
Protein Cell
; 6(10): 774-9, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26264490
20.
On the role of the R configuration of the reaction-intermediate isostere in HIV-1 protease-inhibitor binding: X-ray structure at 2.0 A resolution.
Acta Crystallogr D Biol Crystallogr
; 62(Pt 5): 489-97, 2006 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-16627941