Detalhe da pesquisa
1.
A mouse model featuring tissue-specific deletion of p53 and Brca1 gives rise to mammary tumors with genomic and transcriptomic similarities to human basal-like breast cancer.
Breast Cancer Res Treat
; 174(1): 143-155, 2019 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-30484104
2.
Mutant PIK3CA accelerates HER2-driven transgenic mammary tumors and induces resistance to combinations of anti-HER2 therapies.
Proc Natl Acad Sci U S A
; 110(35): 14372-7, 2013 Aug 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-23940356
3.
Luminal progenitor and fetal mammary stem cell expression features predict breast tumor response to neoadjuvant chemotherapy.
Breast Cancer Res Treat
; 149(2): 425-37, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25575446
4.
Cell-cycle inhibition and immune microenvironment in breast cancer treated with ribociclib and letrozole or chemotherapy.
NPJ Breast Cancer
; 10(1): 20, 2024 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38448600
5.
Transcriptomic changes underlying EGFR inhibitor resistance in human and mouse models of basal-like breast cancer.
Sci Rep
; 12(1): 21248, 2022 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36482068
6.
Comparative expression analysis of the phosphocreatine circuit in extant primates: Implications for human brain evolution.
J Hum Evol
; 60(2): 205-212, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21190724
7.
A potential role for glucose transporters in the evolution of human brain size.
Brain Behav Evol
; 78(4): 315-26, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21986508
8.
Highly metastatic claudin-low mammary cancers can originate from luminal epithelial cells.
Nat Commun
; 12(1): 3742, 2021 06 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34145248
9.
The MMTV-Wnt1 murine model produces two phenotypically distinct subtypes of mammary tumors with unique therapeutic responses to an EGFR inhibitor.
Dis Model Mech
; 12(7)2019 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31213486
10.
Overview of Genetically Engineered Mouse Models of Distinct Breast Cancer Subtypes.
Curr Protoc Pharmacol
; 72: 14.38.1-14.38.11, 2016 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26995547
11.
Genomic profiling of murine mammary tumors identifies potential personalized drug targets for p53-deficient mammary cancers.
Dis Model Mech
; 9(7): 749-57, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27149990
12.
c-Jun N-terminal kinase 2 prevents luminal cell commitment in normal mammary glands and tumors by inhibiting p53/Notch1 and breast cancer gene 1 expression.
Oncotarget
; 6(14): 11863-81, 2015 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25970777
13.
Endothelial-like properties of claudin-low breast cancer cells promote tumor vascular permeability and metastasis.
Clin Exp Metastasis
; 31(1): 33-45, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23975155
14.
Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts.
Genome Biol
; 14(11): R125, 2013 Nov 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24220145
15.
Conditional loss of ErbB3 delays mammary gland hyperplasia induced by mutant PIK3CA without affecting mammary tumor latency, gene expression, or signaling.
Cancer Res
; 73(13): 4075-85, 2013 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23633485
16.
Oncogenic PI3K mutations lead to NF-κB-dependent cytokine expression following growth factor deprivation.
Cancer Res
; 72(13): 3260-9, 2012 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22552288
17.
Comparative oncogenomics implicates the neurofibromin 1 gene (NF1) as a breast cancer driver.
Genetics
; 192(2): 385-96, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22851646
18.
LKB1/STK11 inactivation leads to expansion of a prometastatic tumor subpopulation in melanoma.
Cancer Cell
; 21(6): 751-64, 2012 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-22698401
19.
Combined PI3K/mTOR and MEK inhibition provides broad antitumor activity in faithful murine cancer models.
Clin Cancer Res
; 18(19): 5290-303, 2012 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22872574
20.
A pipeline to determine RT-QPCR control genes for evolutionary studies: application to primate gene expression across multiple tissues.
PLoS One
; 5(9)2010 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-20824057